摘要
目的为了更好的控制产品质量,建立安肾丸的质量标准。方法采用薄层色谱法对制剂中的肉苁蓉、补骨脂、白术进行了定性鉴别,并采用高效液相色谱法测定苦杏仁苷。结果薄层色谱中的特征斑点明显。苦杏仁苷在10.25～512.50μg线性关系良好(r=0.9999),平均回收率为99.78%,RSD值为1.16%(n=6)。结论建立的方法专属性强、重复性好,准确简便,可有效地控制安肾丸的质量。
Objective To establish a quality standards for the quality control of Anshen Pill.Methods The qualitative identification of Cistanches Herba,Psoraleae Fructus,and Atractylodis Macrocephalae Rhizoma in the preparation was carried out by TLC,and the content of amygdalin was determined by HPLC.Results The TLC characteristic spots were quite clear.The linearity range of amygdalin was 10.25—512.50μg （r=0.999 9）,and the average recovery was 99.78% with RSD of 1.16% （n=6） by HPLC.Conclusion The established method is specific,reproducible,and suitable for the quality control of Anshen Pill.
出处
《现代药物与临床》
CAS
2013年第1期47-50,共4页
Drugs & Clinic
关键词
安肾丸
肉苁蓉
补骨脂
白术
薄层色谱
苦杏仁苷
高效液相色谱
Anshen Pill
Cistanches Herba
Psoraleae Fructus
Atractylodis Macrocephalae Rhizoma
TLC
amygdalin
HPLC
