湖北省荆门地区2011年药品不良反应报告分析

Analysis of the Adverse Drug Reaction Reports in Jingmen Area in 2011

目的:分析湖北省荆门地区2011年药品不良反应(ADR)发生特点,促进临床合理用药。方法:查阅荆门地区2011年各报告单位上报国家药品不良反应监测中心ADR报告1 166份,分别统计报告单位、患者年龄、不良反应类型、药品种类、结果评价等项目并分析。结果:1 166例中自医疗机构的报告占98.8%;ADR患者男女比例相当;静滴引起的ADR占86.7%;抗感染药物引起的ADR占59.1%,其中以头孢菌素类发生的ADR最多;消化系统的ADR最多,占33.2%;评价结果为可能的ADR最多,占44.5%;百万人口ADR的发生率为393例。结论:各报告单位要不断提高报告质量,保证临床用药安全、有效。

Objective：To analyze the ADR characteristics of Jingmen area and promote clinical rational drug use. Methods：The report units,ages,types of ADRs,drug varieties and result evaluation were analyzed from 1 166 ADR reports in Jingmen area.Results：Most of the 1 166 reports came from medical institutions（98.8%） and the male and female were equivalent in number.More ADRs came from intravenous drip（86.7%）,59.1%was caused by anti-infective agents,most ADRs came from the digestive system（33.2%）,the incidence of which was 393 cases per million population. Conclusion：The report quality should be constantly improved to ensure clinical rational drug use.