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阿尔兹海默病的血管因素 被引量：7

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摘要 近年来血管因素在阿尔兹海默病(AD)的发生、发展中越来越受到关注。AD患者具有血管扭曲、室周静脉壁胶质增生、血管淀粉样变等血管病理结构改变;有肯定的如高血压、糖尿病、肥胖等血管危险因素。神经血管单元和血脑屏障的破坏可导致淀粉样蛋白在脑内的沉积,在AD发病机制中起着重要作用;脑血流量下降以及脑血管反应性的下降均反映AD患者脑血管的"不健康"状态。
作者 高永哲 章军建
机构地区 武汉大学中南医院神经科
出处 《国际神经病学神经外科学杂志》 2012年第6期558-561,共4页 Journal of International Neurology and Neurosurgery
基金 国家自然科学基金面上项目(30970962)
关键词 阿尔兹海默病 脑血管病理 血管性危险因素 血脑屏障 脑血流量 脑血管反应
分类号 R749.16 [医药卫生—神经病学与精神病学]
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参考文献26

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二级参考文献36

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国际神经病学神经外科学杂志
2012年 第6期

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