百草枯中毒肺损伤的MSCT表现特征与预后相关性分析

Comparative study on MSCT manifestation of the lung damage of paraquat poisoning and clinical prognosis

目的探讨百草枯中毒肺损害MSCT表现及临床预后。方法对百草枯中毒患者的肺部分别进行MSCT检查,并回顾性分析62例患者的CT表现及临床资料。结果百草枯中毒时肺实质、肺间质均受累,43例出现了磨玻璃征、部分患者肺外周出现肺实变,肺气肿及胸水;晚期肺纤维化是主要特征。62例患者肺部CT表现与中毒剂量、检查时间相关。结论百草枯中毒肺部损害具有明确MSCT表现特征。早、中期以肺实质损害为主要CT表现,晚期以肺间质损害为主要CT表现。MSCT对判断肺损害、评估临床预后及制订治疗方案有重要意义。

Objective To investigate the multi-slice spiral CT（MSCT） manifestation of lung damage poisoned by paraquat and clinical prognosis.Methods The chest MSCT was performed in 62 patients with paraquat poisoning.The MSCT manifestation of the lung damage of paraquat poisoning and clinical data in 62 patients with lung damage poisoned by paraquat were retrospectivew analysed.Results The pulmonary parenchyma and pulmonary interstitial were both involved with paraquat poisoning.There were 43 cases with lung damage poisoned by paraquat,which showed ground-glass sign,some patients showed pulmonary consolidation shadow with pulmonary peripheral distribution,pleural fluid effusion and emphysema;the main performance was pulmonary interstitial fibrosis in later stage.The lung CT performance of 62 patients were related to toxic dose and checking time.Conclusion The lung damage of paraquat poisoning has definite MSCT image characteristics.Pulmonary parenchyma damage is CT performance at early and middle state,pulmonary interstitial damage is main MSCT performance at later stage.MSCT scanning has an important significance in finding of lung injury,evolution of prognosis and conduction of therapeutic schemes.