妊娠合并血小板减少55例临床分析

Clinical Analysis of 55 Thrombocytopenia in Pregnancy

目的探讨妊娠期血小板减少的原因及临床处理对策。方法回顾性分析2008年1月～2010年12月55例妊娠合并血小板减少患者的临床资料。结果妊娠合并血小板减少的患者占同期分娩产妇的1．10％。妊娠期特发性血小板减少症（PAT）25例，原发性免疫性血小板减少症（ITP）13N，骨髓增生异常综合征（MDS）6例，营养性巨幼细胞性贫血（NMA）4例，子痫前期、HELLP综合症2例，系统性红斑狼疮（SLE）1例，不明原因4例。55例全部病例中孕产妇死亡1例，产妇颅内出血1例，新生儿血小板减少3例，新生儿死亡2例。结论妊娠期血小板减少原因较多，临床应根据不同病情进行不同的处理。

Objective To investigate the cause and management of pregnant women with thrombocytopenia. Methods The outcome of 55 pregnant with thrombocytopenia was analysed respectively from 2008.1 to 2010.12.Results The rate of thrombocytopenia during pregnant was 1.10%.Among all of cases,25 cases were gestational thrombocytopenia,13 cases were idiopathic thrombocytopenia,6 cases were myelodysplastic syndromes,4 cases were megaloblastic anemia,2 cases were preedampsia,HELLP syndrome,1 case was systemic lupus erythematosus,4 cases were unexplanined. 1 case maternal death,1 case pregnant occurred intracranial hemorrhage,thrombocytopenia occurred in three natals.2 cases newborn mortality.Conclusion Pregnant thrombocytopenia are numerical.We should choose the management according to the differed causes.