血液灌流治疗混配农药中毒48例临床分析

Clinical Analysis of 48 Patients with Mixed Pesticide Poisoning Treated by Hemoperfusion

目的:观察血液灌流治疗混配农药中毒的方法及其临床疗效。方法:将2010年4月至2011年12月我科收治的混配农药中毒患者96例随机分为常规组和血液灌流组各48例,比较两组恢复自主意识时间、住院时间、阿托品用量及疗效。结果:血液灌流组患者恢复自主意识时间、住院时间、阿托品用量均显著低于常规组(P<0.05),血液灌流组治愈率95.8%明显高于常规组的72.9%(P<0.05)。结论:血液灌流治疗混配农药中毒能提高患者生存率,促进患者意识恢复,减少住院时间,不良反应少且操作简单,值得推广应用。

Objective： To observe the method and clinical efficacy of hemoperfusion in the treatment of patients with mixed pesticide poisoning. Methods： 96 patients with mixed pesticide poisoning were divided into conventional group and hemoperfusion group randomly from Apr 2010 to Dec 2011, and each group was 48 cases. The independent consciousness recovery time, hospitalization duration, atropine dosage and curative effect were compared between the two groups. Results： The independent consciousness recovery time, hospitalization duration, atropine dosage were significantly lower in the hemoperfusion group than those in the conventional group （P〈0.05）, but the clinical cure rate in the hemoperfusion group was significantly higher than that in the conventional group, （95.8% ＆72.9%, P 〈 0.05 ）. Conclusion： It is worthy of popularization and application that hemoperfusion can greatly raise survival rate, promote consciousness recovery and reduce the hospitalization duration of patients with mixed pesticide poisoning and less adverse reaction and simple operation.