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276例婴幼儿腹泻病例轮状病毒抗原检测 被引量:2

Result Analysis of Rotavirus Antigens Causing 276 Infants with Diarrhoea
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摘要 目的了解我院儿科腹泻病患轮状病毒抗原感染的情况。方法采用免疫胶体金法对我院2010-08~2011-08秋、冬季276例婴幼儿粪便标本中轮状病毒抗原检测,并根据不同年龄段进行结果分析。结果 276例婴幼儿粪便轮状病毒抗原检测中,阳性率为45.05%,其中0~5个月组阳性率为17.1%,6个月~2岁组阳性率为78%,2~3岁组阳性率为4.9%。结论轮状病毒抗原是导致婴幼儿腹泻最主要的原因之一,通过对此抗原的检测,为临床医师进行病毒治疗提供参考依据,同时也避免抗生素的滥用。 Objective To understand pediatric diarrhea with rotavirus antigen infection of immune colloidal gold.Methods Using immune colloidal gold method to test 276 cases of infants with rotavirus antigen in stool specimens in winter and the fall from August 2010 to August 2011,and doing results analysis according to different ages.Results In 276 cases of infants with rotavirus antigen detection in stool,the positive rate was 45.05%,with 17.1% positive rate in 0~5 months,78% positive rate in 6 months^2 years,and 4.9% in 2 years old-3 years old infants.Conclusion The rotavirus antigen is the leading cause of infant diarrhea.The detection of antigens not only provides references for viral therapy for clinicians,but also avoids the abuse of antibiotics.
出处 《黑龙江医学》 2012年第12期899-900,共2页 Heilongjiang Medical Journal
关键词 轮状病毒抗原 婴幼儿腹泻 粪便 胶体金法 Rotavirus antigen Infants with diarrhea Stool Colloidal gold method
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  • 1中国腹泻病诊断治疗方案[J].临床儿科杂志,1994,12(3):148-151. 被引量:459
  • 2张宏伟,徐晓华,刘凤霖,夏志伟,司徒爱明,张书红,魏博涛,赵煜.天津市儿童医院住院腹泻患儿星状病毒感染检测分析[J].中国实用儿科杂志,2005,20(12):741-742. 被引量:12
  • 3[3]Glass RI,Noel J,Mitechell D,et al The changing epidemiolo-gy of astrovirus associated gastroenteritis:a review[J].Arch Virol,1996,12:287-300.
  • 4Iturriza-Gomara M,Anderton E,Kang G,et al.Evidence for genetic linkage between the gene segments encoding NSP4 and VP6 proteins in common and reassortant human rotavirus strains[J].J Clin Microbiol,2003,41(8):3566-3573.
  • 5Graham KL,Halasz P,Tan Y,et al.Integrin-using rotaviruses bind alpha2beta1 integrin alpha2 I domain via VP4 DGE sequence and recognize alphaXbeta2 and alphaVbeta3 by using VP7 during cell entry[J].J Virol,2003,77(18):9969-9978.
  • 6Dong Y,Zeng CQ,Ball JM,et al.The rotavirus enterotoxin NSP4 mobilizes intracellular calcium in human intestinal cells by stimulating phospholipase C-mediated inositol 1,4,5-trisphosphate production[J].Proc Natl Acad Sci USA,1997,94(8):3960-3965.
  • 7Charpilienne A,Lepault J,Rey F,et al.Identification of rotavirus VP6 residues located at the interface with VP2 that are essential for capsid assembly and transcriptase activity[J].J Virol,2002,76(15):7822-7831.
  • 8Oka T,Nakagomi T,Nakagomi O.A lack of consistent amino acid substitutions in NSP5 between rotaviruses derived from diarrhea and asymptomatically-infected kittens[J].Microbiol Immunol,2001,45(2):173-177.
  • 9Azim T,Zaki MH,Podder G,et al.Rotavirus-specific subclass antibody and cytokine responses in Bangladeshi children with rotavirus diarrhoea[J].J Med Virol,2003,69(2):286-295.
  • 10Cuadras MA,Feigelstock DA,An S,et al.Gene expression pattern in Caco-2 cells following rotavirus infection[J].J Virol,2002,76(9):4467-4482.

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