运动对血清脂联素水平影响的研究现状

Research Status of the Influence of Exercise on Adiponectin Level

脂联素是脂肪细胞分泌的一种细胞因子,具有增强脂肪酸的氧化、提高肌肉葡萄糖摄取、改善胰岛素抵抗、抗动脉粥样硬化、抗炎等作用,通过PPARα和AMPK信号通路发挥作用。脂联素在健康人体血清中含量丰富,在肥胖及2型糖尿病患者中含量降低。运动对脂联素水平影响未取得一致的研究结果,寻找一个有效干预脂联素水平的运动处方是一个值得关注的问题。

Adiponectin is a kind of cytokine from adipocyte,which can play a role in fatty acid oxidation,glucose uptake of muscle,insulin resistance,anti-atherosclerosis and auti-inflammation,and may work through PPARα signaling and AMPK signaling.Adiponectin is abundantly distributed in the blood serum of healthy body,but its level decreases in obesity patients and type 2 diabetic patients.One must pay close attention to looking for effective exercise prescription interfering with adiponectin level,because there is no consistent result on exercise and adiponectin level.