摘要
扫描电化学显微镜(SECM)以其极高的空间分辨率、操作简单、测试样品更接近实际应用情况等特点,近年来逐渐成为生物样品分析中的重要工具,在研究细胞形貌、氧化还原活性、细胞膜上活性位以及跨细胞膜的物质传递方面具有优异的性能。本文介绍了扫描电化学显微镜的工作原理及其在细胞分析、酶分析、DNA分析、抗体抗原分析及微修饰等方面的应用,并展望了该技术未来的发展方向。
Scanning electrochemical microscopy （SECM） has gradually become an important tool in the analysis of biological samples in recent years due to its high spatial resolution, simple operation and the test samples closer to the actual application characteristics. The technology has superior performance in cell morphology imaging, redox activity analysis, and the active sites on the cell membrane and cross the cell membrane mass transfer. The working principle of SECM and its application in cell analysis, enzyme analysis, DNA analysis, antibody-antigen analysis and micro-modification were introduced. The future development direction of the technology was forecast.
出处
《化学通报》
CAS
CSCD
北大核心
2013年第2期124-131,共8页
Chemistry
关键词
扫描电化学显微镜
原理
细胞分析
酶分析
Scanning electrochemical microscopy（SECM） , Principle, Cell analysis, Enzyme analysis
