中医补肾泄浊法与包醛氧淀粉治疗慢性肾功能衰竭的Meta分析

Meta-analysis of Treatment of Chronic Renal Failure by Traditional Chinese Medicine Bushen Xiezhuo Method and Oxyamyli Tectus Aldehydum

目的:以循证医学系统评价方法 Meta分析为依据客观评价中医补肾泄浊法治疗慢性肾功能衰竭的疗效及安全性。方法:检索国内各种医学期刊杂志,选择中医补肾泄浊法与包醛氧淀粉治疗慢性肾功能衰竭的随机对照的试验研究。共纳入13篇符合纳入标准的随机对照临床试验并进行Meta分析。结果:与包醛氧淀粉相比,补肾泄浊法在治疗慢性肾功能衰竭在总体疗效,降低血肌酐、血尿素氮等方面优于包醛氧淀粉治疗组。结论:补肾泄浊法治疗慢性肾功能衰竭的疗效优于包醛氧淀粉,但还需要设计良好的随机对照及多中心临床试验做进一步证实。

Objective： Evidence-based Meta-analysis was used to evaluate efficacy and safety in the treatment of chronic renal failure by traditional Chinese medicine Bushen Xiezhuo method. Method： Retrieval of domestic medical journals was made, and Chinese medicine Bushen Xiezhuo method with Oxyamyli teetus Aldehydum was chosen in the treatment of chronic renal failure randomized controlled experimental study. 13 randomized controlled clinical trials and Meta-analysis were selected. Result： Compared with Oxyamyli teetus Aldehydum, Bushen Xiezhuo method in the treatment of chronic renal failure in overall efficacy, lower serum creatinine and blood urea nitrogen are superior to that of oxyamyli tectus aldehydum treatment group. Conclusion： Bushen Xiezhuo method in the efficacy of treating chronic renal failure is superior to oxyamyli teetus aldehydum, but needs to be well designed randomized controlled multieenter clinical trial and further confirmed.