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高能聚焦超声刀治疗晚期胰腺癌疼痛208例临床观察 被引量:8

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摘要 目的:探讨高能聚焦超声刀治疗晚期胰腺癌疼痛的疗效及安全性。方法:对208例伴有疼痛的晚期胰腺癌患者给予高能聚焦超声刀治疗,观察疼痛缓解情况、不同时间点KPS评分变化以及并发症发生情况。结果:治疗后1周、1个月及3个月,总缓解率分别为77.4%、75.9%和48.9%。精神、睡眠、营养状况等有所改善,1个月后及3个月后KPS评分较治疗前明显改善(P<0.05)。23例(11.1%)患者出现局部皮肤硬结,26例(12.5%)出现治疗部位烧灼样疼痛,8例(3.8%)出现肢体远端湿冷、出虚汗、心慌,5例(2.4%)出现轻度消化道并发症,经对症治疗后,短期内好转。结论:高能聚焦超声刀是一种安全、有效的治疗晚期胰腺癌疼痛的辅助治疗手段,并能有效地改善患者的生活质量。
出处 《南京医科大学学报(自然科学版)》 CAS CSCD 北大核心 2012年第12期1707-1710,共4页 Journal of Nanjing Medical University(Natural Sciences)
基金 江苏省医学重点学科基金资助(XK 200718) 江苏省卫生厅重点项目(H200110)
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参考文献11

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