昆仑雪菊黄酮类成分研究

Study on Flavonoids of Coreopsis tinctoria Nutt

采用大孔树脂、ODS RP-18和Sephadex LH-20柱从昆仑雪菊中分离得到7个黄酮类化合物,通过理化性质和波谱学方法鉴定化合物的结构,分别为:异奥卡宁7-O-β-吡喃葡萄糖苷(1)、栎草亭-7-O-β-D-吡喃葡萄糖苷(2)、马里苷(3)、奥卡宁(4)、木犀草素(5)、槲皮素(6)、8-羟基黄颜木素(7)。其中化合物2、5、6和7为首次从该植物中分离得到。

Seven chemical compounds were isolated and purified from Coreopsis tinctoria Nutt using different kinds of col- umn chromatography. Their structures were determined as isookanin 7-O-β-D-glucopyranoside （1）, quercetagetin-7-O-β- D-glucopyranoside （2）, marein （3）, okanin （4）, luteolin （ 5）, quercetin （6）, dihydromelanoxetin （ 7 ） on the basis of the physicochemical properties and spectral analysis. Compound 2,5,6 and 7 were obtained from this plant for the first time.