湖北省某市恶性肿瘤死亡所致疾病负担研究

Study of the disease burden associated with malignant tumor mortalities in a city of Hubei province

目的分析湖北省某市(以下简称样本地区)居民恶性肿瘤疾病分布、死亡状况,了解该类疾病早死所造成的疾病负担,为制定科学合理的防治政策和措施提供依据。方法选择样本地区2007年的死因监测资料,以恶性肿瘤早死所致的潜在减寿年数(potential years loss of life,PYLL)、死亡损失生命年(years of life lost,YLL)及相关指标作为该类疾病负担的测量单位,比较其分布特点和变化规律。结果样本地区人群恶性肿瘤死亡率为1.28‰,恶性肿瘤死亡人数占总死亡人口的28.44%。恶性肿瘤居全死因的第2位。男性恶性肿瘤死亡率高于女性。居于前5位的恶性肿瘤依次是气管、支气管、肺,肝,胃,食管,结肠肿瘤,死亡人数占全部恶性肿瘤死亡人数的74.17%。男女性别居于前3位的恶性肿瘤相同,分别是气管、支气管、肺,肝,胃肿瘤。样本地区恶性肿瘤导致的潜在减寿年数合计为4 084.9。结论 2007年恶性肿瘤是样本地区居民死亡的主要原因,男性高于女性,气管、支气管、肺,肝脏,胃,食管是本地区恶性肿瘤预防控制工作的重点。

Objective To analyze the distribution and mortalities of malignant tumors in a city of Hubei province, to study the disease burden and to provide the basis for prevention and treatment measures. Methods The data of death in 2007 were used. The potential years loss of life （PYLL） and years of life lost （YLL） associated with malignant tumors were served as indexes of disease burden. The regular pattern of distribution and change for those indexes was analyzed. Results The mortality of malignant tumor of general population in present area was 1.28 %0, the proportion of malignant tumor mortality was 28.44%. The malignant tumor was the second position in death cause ranking. The malignant tumor mortality of the males was higher than that of the females. The mortality order of malignant tumor was trachea, bronchus, lung, liver, stomach, esophagus and colon cancers. The proportion of those cancers in malignant tumor mortality was 74.17%. The cancers with the highest mortalities in males and females were the trachea, bronchus and lung cancers or the liver, stomach and esophagus cancers, respectively. PYLL caused by malignant tumors in present area was a total of 4 084.9 person-years. Conclusion The main death cause in present area is malignant tumors in 2007. The mortality of malignant tumors in the males is higher than that in the females. The prevention and control of malignant tumors should focus on the trachea, bronchus, lung, liver, stomach and esophagus cancers.