机械通气治疗肠道病毒71型感染危重症手足口病临床研究与救治体会

The Clinical Analysis and Treatment Learning of Mechanical Ventilation for the Severe Hand, Foot and Mouth Disease Infected by Enterovirus 71

目的:探讨机械通气治疗重症手足口病患儿的效果。方法:对35例重症手足口病患儿在应用常规药物治疗的同时予机械通气,根据病情调整呼吸机参数,观察通气前后临床症状及相关指标变化,并记录患儿住院天数、机械通气时间、转归及并发症发生等情况。结果:35例患儿平均住院时间(12.44±2.29)d,平均机械通气时间(3.34±1.44)d,共有30例患儿治愈或好转,机械通气后患儿体温、呼吸、心率、血压值及血氧饱和度较治疗前均有显著改善(P<0.05)。结论:重症手足口病患儿应仔细密切关注病情变化,经常规治疗后如症状不能改善,须尽早使用机械通气治疗,同时予以药物及对症支持处理。

Objective：Analyzing the clinical effects of mechanical ventilation for the severe hand, foot and mouth disease children. Methods.mechanical ventilation was used for 35 cases of severe hand, foot and mouth disease, the breathing machine parameter were regulate based on the patient＇s condition. The clinical syndromes were observed before and after the mechanical ventilation treatment. The time in hospital, time of mechanical ventilation, prognosis of disease and complication were also recorded. Results： The mean time in hospital was （12.44 ＋ 2.29）d, and mean time for mechanical ventilation was （3.34 ± 1.44）d. 30 children were re- covered or improved. The body temperature, breath rate, heart rate, blood pressure value and saturation of blood oxygen were im-proved significantly after treatment. Conclusion ： Severe hand-foot-mouth disease children should carefully be paid close attention for the condition changes. If conventional treatment can not improve the condition, mechanical ventilation treatment, drug as well as supportive treatment should be used for the treatment.