腔镜甲状腺手术68例临床观察

Endoscopic thyroidectomy in 68 cases

目的比较甲状腺腔镜手术与传统开放手术的临床疗效。方法回顾性分析2011年5月至2012年5月云南省第二人民医院行甲状腺手术的136例患者，其中68例采用腔镜甲状腺手术（腔镜组），68例采用传统手术（传统组）治疗，分别比较2组的手术时间、术中出血量、术后引流量、血清白介素-2（IL-2）、C反应蛋白（CRP）、肿瘤坏死因子（TNF-α）表达水平、并发症、住院天数等指标。结果2组在手术时间、术中出血量、术后引流量、血清IL-2、CRP、TNF—α表达水平、并发症等方面差异无统计学意义（P〉0．05）。但腔镜组在术后住院天数、颈部不适感及手术接受程度等方面明显优于传统组，差异有统计学意义（P〈0．05）。结论腔镜甲状腺手术与传统手术相比安全、可靠，不增加手术创伤，在美容方面具有不可比拟的优点。

Objective To compare the clinical therapeutic effects of thyroid endoscopic surgery and traditional open surgery in treatment of thyroid diseases. Methods Data of 136 patients undergoing thyroid surgery from May. 2011 to May. 2012 in the Second People＇s Hospital of Yunnan Province were collected. They were randomly divided into 2 groups ： the observation group （ n = 68 ） and the control group （ n = 68 ）. The observation group were treated with endoscopic thyroid surgery and the control group with the traditional surgery. Clinical data of the 2 groups such as operation time, intraoperative blood loss, postoperative drainage volume, postoperative se- rum interleukin 2 （ IL-2 ）, C reaction protein（ CRP）, TNF- αexpression level, postoperative complications, post- operative hospital stay and so on were collected and compared. Results The difference had no statistical significance between the 2 groups in the operation time, intraoperative blood loss, postoperative drainage volume, post- operative serum IL-2, CRP, TNF- α expression levels, and postoperative complications （ P 〉 0.05）. However, the observation group had superiority in the postoperative hospital stay, neck discomfort and the acceptability than the control group. The difference had statistical significance （ P 〈 0. 05 ）. Conclusions Endoscopic thyroid surgery is safe and reliable. Compared with traditional open surgery, it has better cosmetic effects and less trauma.