Vitapex在乳牙根管治疗中疗效的循证医学分析

Meta-analysis of the effectiveness of Vitapex in root canal therapy of deciduous teeth

目的评价Vitapex在乳牙根管治疗中的疗效。方法通过Cochrane系统评价的方法,计算机和手工方法检索数据库中关于乳牙根管治疗的临床文献,采用Revman 4.2对纳入的国内研究进行Meta分析。结果共找到292篇文献,最终18篇纳入标准。分析结果表明:Vitapex充填根管的0.5、1年效果可以合并且均优于对照组,差异具有统计学意义(P<0.05);而Vitapex充填根管的两年效果的数据存在统计学异质性不可以合并,但疗效有优于对照组的趋势。结论 Vitapex在乳牙根管治疗中是一种理想的材料。

Objective To evaluate the effectiveness of Vitapex on root canal therapy on deciduous teeth. Methods The Coehrane reviewer hand book was followed. The papers and documents on the clinical effectiveness of Vitapex on data bases were searched and collected by computer and hand-search, the Meta-analysis was also done on the findings with Revman 4.2 software. Results Eighteen among 292 papers were collected. The effectiveness of Vitapex in 0.5 and 1 year could be merged and was higher than the control group, and the difference was statistically significant. The effectiveness of Vitapex in 2 year could not be combined, for significant heterogeneity was found. So only the descriptive analysis could be used. The 2 years＇ efffectiveness had a trend which was superior to the control group. Conclusion For deciduous teeth, Vitapex paste is an excellent filling material.