自身免疫性大疱性皮肤病评分系统在天疱疮治疗中的应用

The application of autoimmune bullous skin disorders intensity score in the treatment of pemphigus

天疱疮是一类严重的、慢性皮肤-黏膜大疱性疾病,糖皮质激素是其治疗的首选药物,但长期用药可能导致较严重的并发症甚至死亡。近年来,国外学者提出一系列天疱疮评估系统,有助于较准确评估病情、客观评价药物疗效、监测病情转归等。本文将重点介绍较受公认的自身免疫性大疱性皮肤病评分系统,并根据临床实践对其提出思考和改进意见。

Pemphigus is a kind of serious, chronic skin-mucosa bullous disorder. Glucocorticoid, as the first choice drug, could reduce the mortality of the disease largely, while long-term use could lead to fatal adverse reaction. Series of evaluation system have been put forward by foreign scholars, which contribute significantly to disease and drug efficacy assessment and monitoring. Autoimmune bullous skin disorders intensity score system in this paper is a relatively accepted system, and some suggestions for improvement would be put forward according to our clinical practice