知晓癌症病情对胃肠道恶性肿瘤患者生活质量的影响

The impact of knowing cancer diagnosis on quality of life in patients with gastrointestinal malignant tumor

目的 探讨知晓癌症病情对胃肠道恶性肿瘤患者生活质量的影响及影响胃肠道恶性肿瘤患者生活质量的因素.方法 采取方便抽样方法,选取唐山市4家三级甲等综合医院明确诊断为胃肠道恶性肿瘤,未接受放、化学治疗的癌症患者130例,根据患者知晓癌症病情情况分为知晓病情组（62例）和不知晓病情组（68例）.应用欧洲癌症研究与治疗组织开发的生活质量测评量表（EORTC QLQ-C30）中文版进行调查.结果 在130名胃肠道恶性肿瘤患者中,知晓和不知晓癌症病情两组间患者的总体健康状况、躯体功能、角色功能、情绪功能和认知功能的评分差异均无统计学意义（P＞0.05）;知晓病情组的社会功能[（45.8±24.2）分]低于不知晓病情组[ （73.0±16.2）分],疲乏[（55.8±26.2）分]和经济困难[（38.2±35.1）分]高于不知晓病情组[（41.8±10.2）分]和[（12.00±10.0）分],差异有统计学意义（P＜0.01）;在多元逐步回归中,躯体功能和疲乏是影响胃肠道恶性肿瘤患者生活质量的因素（P＜0.05）.结论 知晓癌症病情不影响胃肠道恶性肿瘤患者的生活质量.

Objective To explore the difference in quality of life in patients with gastrointestinal cancer between those who knew cancer diagnosis and those who did not.Methods 130 patients with recently diagnosed gastrointestinal cancer in 4 general hospitals in Tangshan were interviewed. Patients were categorized into two groups：one group was those who knew their diagnosis（n=62） and the other group was those who did not （ n =68）.The Chinese version of European Organization for Research and Treatment （EORTC） quality of life （QOL）questionnaire （QLQ-C30） was used.Results The comparison of quality of life between patients who knew their diagnosis and those who did not indicated that the score of global quality of life and other functional scales including physical,emotional,role and cognitive functioning did not show significant difference（P 〉 0.05 ）.Compared with those who did not know cancer diagnosis,patients who were aware of diagnosis showed a significant lower degree of social functioning （ （45.8 ± 24.2 ） vs （ 73.0 ± 16.2 ） ）,a significant higher degree of fatigue （ （ 55.8 ±26.2） vs （41.8 ±10.2） ） and financial difficulties （（38.2 ±35.1） vs （12.00 ±10.0） ） （P〈0.01）.In multiple regression analysis,physical functioning and symptom of fatigue had statistically significant differences （P〈 0.05 ）.Conclusion The knowledge of cancer diagnosis does not contribute to the quality of life in patients with gastrointestinal cancer.