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棘形红细胞尿对糖尿病肾病与非糖尿病肾病鉴别诊断的临床意义研究 被引量:2

Clinical value of acanthocyturia in differential diagnosis of diabetic nephropathy and nondiabetic renal disease
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摘要 目的探讨棘形红细胞尿对糖尿病肾病(DN)与非糖尿病肾病(NDRD)鉴别诊断的临床意义以期指导临床。方法对在我科及肾内科住院诊治的22例合并有血尿的DN患者与33例合并有血尿的NDRD患者的尿棘形红细胞进行相差显微镜观察计数,并进行对比研究;所有病例均行肾穿刺活检术提供病理学依据。结果 NDRD组及DN组的棘形红细胞尿的检出率分别为:69.5%和4.5%,两者相比具有统计学意义。结论合并血尿的DM患者出现肾功能损害时,若发现棘形红细胞尿则考虑可能合并NDRD,需要尽快行肾穿刺活检术以明确其病理类型,以便指导临床治疗。 Objective To investigate the clinical value of acanthocyturia in differential diagnosis of diabetic nephropathy(DN) and nondiabetic renal disease(NDRD).Methods Acanthocytes in urine of twenty patients of DN and thirty patients of glomerulonephritis with hematuria were observed and compared.All the patients had been given renal biopsy.Results Acanthocyturia was found in 76.7% of patients with glomerulonephritis,in 5.0% of patients with DN(P0.001).Conclusion The finding of acanthocyturia in patients of DN with hematuria points to nondiabetic glomerulopathies,and renal biopsy should be considered.
出处 《福建医药杂志》 CAS 2012年第4期24-25,共2页 Fujian Medical Journal
关键词 棘形红细胞尿 糖尿病肾病 非糖尿病肾病 acanthocyturia diabetic nephropathy nondiabetic renal disease
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参考文献9

  • 1Huang F,Yang Q,Chen L. Renal pathological changes in patients with type 2 diabetes are not always diabetic nephropathy:a report of 52 cases[J].Clinical Nephrology,2007,(05):293-297.
  • 2Tentori F,Stidley CA,Scavini M. Prevalence of hematuria among Zuni Indians with and without diabetes:the Zuni kidney project[J].American Journal of Kidney Diseases,2003,(06):1195-1204.doi:10.1016/S0272-6386(03)00351-2.
  • 3Lopes de Faria JB,Moura LA,Lopes de Faria SR. Glomerular hematuria in diabetics[J].Clinical Nephrology,1988,(03):117-121.
  • 4Kohler H,Wandel E,Brunck B. Acanthocyturia:a characteristic marker for glomerular bleeding[J].Kidney International,1991,(01):115-120.doi:10.1038/ki.1991.188.
  • 5Kitamoto Y,Tomita M,Akamine M. Differentiation of hematuria using a uniquely shaped red cell[J].Nephron,1993,(01):32-36.doi:10.1037/a0017512.
  • 6董秀清,孙玉玲,姜傥,沈丽青,周建中,王昌云.用一种独特形态的红细胞鉴别血尿[J].中华肾脏病杂志,1999,15(5):311-313. 被引量:34
  • 7Olsen S. Identification of non-diabetic glomerular disease in renal biopsies from diabetics-a dilemma[J].Nephrology Dialysis Transplantation,1999,(08):1846-1849.doi:10.1093/ndt/14.8.1846.
  • 8张胜兰,张爱平,邢万佳,郭徽,王艳侠,张秀英,王滨.170例糖尿病肾病肾活检分析[J].中华糖尿病杂志(1006-6187),2005,13(1):46-48. 被引量:10
  • 9Gunnar Heine,Matthias Girndt,Urban Sester. Acanthocytes in the urine useful tool to differentiate diabetic nephropathy from glomerulo-nephritis[J].Diabetes Care,2004,(01):190-194.

二级参考文献12

  • 1李幼姬 叶任高 等.红细胞活体染色后用光镜鉴别血尿来源的新方法[J].中华肾脏病杂志,1985,1(2):74-76.
  • 2凌衫洪 叶任高 等.新的尿红细胞分类计数法鉴别血尿来源[J].中华内科杂志,1994,33:255-257.
  • 3李幼姬 叶任高 等.诊断肾小球性血尿的一种简例方法[J].中华内科杂志,1984,23:99-101.
  • 4凌衫洪,中华内科杂志,1994年,33卷,255页
  • 5Chu Y D,Nephron,1993年,64卷,32页
  • 6Chu Y D,Kumamoto Med J,1990年,42卷,63页
  • 7李幼姬,中华肾脏病杂志,1985年,1期,74页
  • 8李幼姬,中华内科杂志,1984年,23卷,99页
  • 9Mazzucco G, Bertani T, Fortunato M,et al. Different patterns of renal damage in type 2 diabetes mellitus: A mUlticentric study on 393 biopsies, Am J Kidney, 2002,39:713-720.
  • 10Lee ey, Chung CH, Choi SO. Non-diabetic renal disease in patients with non-insulin-dependent diabetes mellitus. Yonsei Med,1999,40: 321-326.

共引文献42

同被引文献20

  • 1周建辉,陈香美,谢院生,李建军,吴杰,蔡广研.糖尿病肾病与非糖尿病性肾脏疾病的对比分析及其诊断概率回归方程的建立[J].中华肾脏病杂志,2005,21(4):182-185. 被引量:25
  • 2de Boer IH, Rue TC, Hall YN, et al. Temporal trends in the prevalence of diabetic kidney disease in the United States [J]. JAMA, 2011,305(24) : 2532-2539.
  • 3Oh SW, Kim S, Na KY, et al. Clinical implications of pathologic diagnosis and classification for diabetic nephropathy [ J ]. Diabetes Res Clin Pract, 2012,97 ( 3 ) : 418-424.
  • 4Tentori F, Stidley CA, Scavini M, et al. Prevalence of hematuria among Zuni Indians with and without diabetes: The Zuni kidney Project [J] Am J Kindey Dis, 2003, 41 (6): 1195-1204.
  • 5Drummond KN, Kramer MS, Suissa S, et al. Effects of duration and age at onset of type 1 diabetes on preclinical manifestations of nephropathy [J]. Diabetes,2003,52 (7) : 1818-1824.
  • 6Chihara J, Takebayashiv S, Taguchi T, et al. Glomerulonephritis in diabetic patients and its effect on the prognosis [J]. Nephron, 1986,43 ( 1 ) : 45-49.
  • 7Heine GI-I, Sester U, Girndt M, et al. Acanthocytes in the urine: useful tool to differentiate diabetic nephropathy from glomerulonephritis? [ J ]. Diabetes Care, 2004, 27 ( 1 ) : 190-194.
  • 8KDOQI Clinical Practice Guidelines and Clinical PracticeRecommendations for Diabetes and Chronic Kidney Dis-ease.American journal of kidney diseases:the official jour-nal of the National Kidney FoundationAmerican journal ofkidney diseases : the official journal of the National KidneyFoundationAm[j]j Kidney Dis,2007,49(2):S12-S154.
  • 9Pocivalnik M,Tsybrovskyy 0,Schwarz C,et al.Role of anti-phospholipase A(2) receptor antibodies in the differentialdiagnosis of diabetic and membranous nephropathy [ J ].Dia-betes Care,2013,36(8):ell4-115.
  • 10Ehren M,Dietrich JW.Woman with type 1 diabetes mellitusand rapidly progressive edema[J].Dtsch Med Wochenschr,2013,138(18):940-944.

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