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人宫颈癌SiHa细胞核维生素D受体的检测 被引量:4

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摘要 目的观察人宫颈癌SiHa细胞内特异性受体——核维生素D受体(nVDR)蛋白和mRNA的表达。方法采用免疫组织化学方法观察人宫颈癌SiHa细胞nVDR蛋白的表达,RT-PCR检测该细胞nVDR mRNA的表达。结果免疫组化法检测SiHa细胞核内表达nVDR蛋白;RT-PCR产物与预期的nVDR的cDNA分子量完全相符。结论人宫颈癌SiHa细胞表达nVDR,为骨化三醇应用于宫颈癌治疗及探索其作用机制提供了基础。
出处 《福建医药杂志》 CAS 2012年第4期73-75,共3页 Fujian Medical Journal
基金 福建省教育厅B类科技项目(JB11078)
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参考文献8

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