肝硬化患者的营养状况评估

Nutritional Assessment in patients with liver cirrhosis

目的旨在通过运用NRS2002对122名肝硬化住院患者的营养风险评估与营养参数分析,为临床医生提供依据,早期发现和早期纠正营养不良,改善患者预后。方法安徽医科大学第一附属医院2010年3月到10月诊断为肝硬化的住院病人122例,在住院第一天进行NRS2002营养风险评估、营养参数指标测量,分为营养不良风险组(NRS≥3)和无营养不良风险组(NRS<3),同时分析营养不良风险组与无营养不良风险组间营养参数指标的差异。结果 122例中有93例肝硬化住院患者存在营养不良风险,营养不良发生率为76%。其中营养不良风险患者中Child-Pugh A级为10人,营养不良发生率为30%(10/30);Child-Pugh B级55人,营养不良发生率为86%(55/64);Child-Pugh C级28人,营养不良发生率100%(28/28)。营养不良发生率与疾病严重程度成正比。对有无营养不良风险的肝硬化病人进行比较,结果显示2组间肝硬化营养指标测定值均有显著差异。结论 NRS2002可用于肝硬化营养风险筛查,肝硬化患者营养不良程度评价需综合分析。旨在通过对122名肝硬化住院患者的营养参数分析,为临床医生提供依据,早期发现和早期纠正营养不良,改善患者预后。

Objective This study aims to assess nutritional parameters of 122 patients with liver cirrhosis and provide useful evidence for the clinician,detecting and correcting malnutrition early,improving the prognosis of patients.Methods Nutritional risk screening（NRS2002）,anthropometry and biochemistry parameters were examined in 122 cirrhotic patients coming from The First Affiliated Hospital of AnHui Medical University.All patients treated with fat emulsion in the period of March,2010 to October,2010 were collected and divided into two groups by NRS2002.Anthropometry and biochemistry parameters were compared between two grades.Results 122 patients completed the study.Malnutrition rate was 76%.Child-Pugh A class of malnutrition risk patients was 10 cases.malnutrition rate was 33%.whereas in Child-Pugh B patients was 86%,in Child-Pugh C class was 100%.The incidence of malnutrition is proportional to the severity of disease.There was a significant difference between the two treatments regarding anthropometry and biochemistry parameters.Conclusion NRS2002 is applicable to nutritional evaluation in patients with liver cirrhosis.The degree of malnutrition in patients with cirrhosis require a comprehensive analysis.