男性酒精依赖者冲动行为与执行功能

Impulsive Behavior and Executive Function of Male Alcohol-dependent Patients

目的探讨男性酒精依赖者冲动行为与执行功能的相关性。方法采用Barratt-11冲动性量表中文版(BIS-11)和威斯康星(WCST)卡片分类测验,对60例男性酒精依赖者进行测试,并与60例正常人作对照研究。结果①依赖组BIS-11总分和各因子分(认知因子、冲动因子、无计划因子)高于正常对照组(t=8.31,10.16,7.046,7.316;P<0.001);②在WCST评分中,依赖组在完成第一类分类所需应答数、错误应答数、持续错误数、总应答数、持续应答数中得分明显高于对照组(t=7.751,13.254,8.370,7.578,6.159;P<0.05),而在完成分类数中的得分低于对照组(t=-6.322,P<0.001);③BIS总分与完成第一分类需要数、WCST的持续应答数与动机性冲动、无计划性冲动呈显著性正相关(r=0.260,0.30,0.253;P<0.05)结论酒精依赖者冲动行为较强烈而执行功能受到抑制。

Objective To explore the correlation between impulsive behavior and executive function of male alcohol-dependent patients.Methods Contrast between 60 patients with alcohol dependence and 60 normal controls with the Barratt Impulsiveness Scale-11 Chinese Version（BIS-11）and Wisconsin Card Sorting Test（WCST）.Results Patients with alcohol dependence had higher BIS-11 total score and each factor score than the normal controls（t=8.31,10.16,7.046,7.316;P0.001）.In the WCST scores,dependent group had significantly higher score of the number of trials to complete the first category,the number of error answers,the number of preservative errors,the number of preservation of responses,the number of total trials than the normal control（t=7.751,13.254,8.370,7.578,6.159;P0.05,while lower score of the number of categories completed（t=-6.322,P0.001）.There was significantly positive correlation among the BIS-11 total score,the number of trials to complete the first category,the number of preservation of responses,impulsiveness and unplanned impulse（r=0.260,0.30,0.253;P0.05）.Conclusion The more intense impulsive behavior the alcohol-dependent patients are,the worse executive function.