天然橡胶胶清化学成分的研究

Chemical Components of the Hevea brasiliensis Skim

对天然橡胶胶清的化学成分进行了研究。运用硅胶柱色谱及葡聚糖凝胶LH-20柱色谱进行化学成分的分离和纯化,用理化方法及波谱手段解析其化学结构。从天然橡胶胶清中分离得到13个化合物,鉴定了其中12个化合物的结构,分别为:木栓酮(Ⅰ)、羽扇豆醇(Ⅱ)、β-谷甾醇(Ⅲ)、棕榈酸(Ⅳ)、硬脂酸(Ⅴ)、胡萝卜苷(Ⅵ)、尼古丁酸(Ⅶ)、琥珀酸(Ⅷ)、没食子酸(Ⅸ)、果糖(Ⅹ)、白坚木皮醇(Ⅺ)和6-hydroxy-cleistopholine(Ⅻ)。经检索,其中化合物Ⅰ、Ⅱ、Ⅵ、Ⅶ、Ⅸ和Ⅻ为首次从天然橡胶胶清中分得。

The chemical constituents of the Hevea brasiliensis skim were studied. Compounds were isolated and purified by silica gel column chromatography and Sephadex LH-20. Their structures were identified by physicochemical properties and spectral analyses. Thirteen compounds were obtained and the twelve ones of them were identified ： Friedelin （Ⅰ）, Lupeol （Ⅱ）,β-Sitosterol （Ⅲ）, Hexadecanoic acid （ Ⅳ）, Heptadecanoic acid （Ⅴ） , Daucosterol （ Ⅵ ）, Nicotine acid （ Ⅶ）, Succinic acid （ Ⅷ）, Gallac acid （Ⅸ）, Fructose （Ⅹ）, Quebrachitol （Ⅺ）, 6-hydroxy-cleistopholine （Ⅻ）. Compounds Ⅰ, Ⅱ, Ⅵ, ⅦIX and Ⅻ were isolated from Hevea brasiliensis skim for the first time.