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microRNA在心血管疾病中的作用及其法医学意义 被引量：4

The Role and Significance of microRNA in Human Cardiovascular Disease and Forensic Science
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摘要 microRNA（miRNA或miR）是一类21～25nt大小的单链非编码RNA，在生物体内广泛存在，并调节基因表达。近年来与心血管疾病发生、发展相关的miRNA不断有报道。本文综述了miRNA的研究进展，从心肌组织和循环血液中的miRNA两方面综述miRNA在心血管疾病中的作用．并探讨miRNA在心源性猝死法医学鉴定中的可能应用。 microRNA （miRNA or miR） is a small single stranded non-coding RNA （21-25nt） that reg- ulates gene expression in almost creatures. Currently, plenty of researches on how miRNA affects human cardiovascular disease have been reported. This review highlights recent findings about the role of miRNA in heart tissue and circulation correlated with human cardiovascular disease and explores the application of miRNA in sudden cardiac death in forensic science.
作者 李立亮 赵子琴
机构地区 复旦大学上海医学院法医学系
出处 《法医学杂志》 CAS CSCD 2013年第1期39-42,共4页 Journal of Forensic Medicine
关键词 法医病理学 微RNAS 综述[文献类型] 心血管疾病 forensic pathology microRNAs review [publication type] cardiovascular diseases
分类号 R54 [医药卫生—心血管疾病]
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共引文献982

同被引文献41

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引证文献4

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法医学杂志
2013年 第1期

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