期刊文献+

细胞移植在肝衰竭治疗中的应用价值

下载PDF
导出
摘要 干细胞和肝细胞移植的应用为肝病患者提供了一条新的治疗途径。该移植术的研究对于肝衰竭和失代偿期肝硬化患者的治疗有着极为重要的意义。本文通过对肝细胞及干细胞移植术介绍和临床应用现状分析,综合评价了两种细胞治疗技术各自的优缺点,并对解决该技术中存在的各种问题进行了探讨。虽然肝细胞移植在肝衰竭的治疗中有重要作用,但还有许多向题有待解决。目前临床应用受到肝细胞来源紧缺、肝细胞冻融后活力降低和移植后免疫排斥等因素的制约,还需要有针对性的进一步研究、发展和探索。
出处 《实用肝脏病杂志》 CAS 2013年第1期22-23,共2页 Journal of Practical Hepatology
  • 相关文献

参考文献1

二级参考文献25

  • 1Fisher RA,Strom SC.Human hepatocyte transplantation:worldwide results.Transplantation 2006; 82:441-449
  • 2Mitry RR,Dhawan A,Hughes RD,Bansal S,Lehec S,Terry C,Heaton ND,Karani JB,Mieli-Vergani G,Rela M.One liver,three recipients:segment IV from split-liver procedures as a source of hepatocytes for cell transplantation.Transplantation 2004; 77:1614-1616
  • 3Habibullah CM,Syed IH,Qamar A,Taher-Uz Z.Human fetal hepatocyte transplantation in patients with fulminant hepatic failure.Transplantation 1994; 58:951-952
  • 4Strom SC,Fisher RA,Thompson MT,Sanyal AJ,Cole PE,Ham JM,Posner MP.Hepatocyte transplantation as a bridge to orthotopic liver transplantation in terminal liver failure.Transplantation 1997; 63:559-569
  • 5Sokal EM.Liver transplantation for inborn errors of liver metabolism.J Inherit Metab Dis 2006; 29:426-430
  • 6Pereira SP,McCarthy M,Ellis AJ,Wendon J,Portmann B,Rela M,Heaton N,Williams R.Auxiliary partial orthotopic liver transplantation for acute liver failure.J Hepatol 1997; 26:1010-1017
  • 7Allen KJ,Soriano HE.Liver cell transplantation:the road to clinical application.J Lab Clin Med 2001; 138:298-312
  • 8Horslen SP,McCowan TC,Goertzen TC,Warkentin PI,Cai HB,Strom SC,Fox IJ.Isolated hepatocyte transplantation in an infant with a severe urea cycle disorder.Pediatrics 2003; 111:1262-1267
  • 9Stephenne X,Najimi M,Smets F,Reding R,de Ville de Goyet J,Sokal EM.Cryopreserved liver cell transplantation controls ornithine transcarbamylase deficient patient while awaiting liver transplantation.Am J Transplant 2005; 5:2058-2061
  • 10Stephenne X,Najimi M,Sibille C,Nassogne MC,Smets F,Sokal EM.Sustained engraftment and tissue enzyme activity after liver cell transplantation for argininosuccinate lyase deficiency.Gastroenterology 2006; 130:1317-1323

共引文献22

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部