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自噬基因Beclin1与肿瘤的关系 被引量:3

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摘要 自噬是一种在进化上保守,亚细胞水平的自我吞噬,形成自噬溶酶体,降解泡内的细胞质及细胞器,释放氨基酸和游离脂肪酸,从而实现细胞的自身代谢和细胞器更新,以适应环境、维持稳态的过程。自噬活性的改变、自噬信号通路和转运途径的负向调控与多种肿瘤的发生、发展密切相关,自噬基因的异常表达能够启动或抑制某些肿瘤的形成。
机构地区 解放军第 解放军第
出处 《国际检验医学杂志》 CAS 2013年第4期458-460,共3页 International Journal of Laboratory Medicine
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