原发性肝癌死亡病例年龄和性别及严重并发症分布规律分析

An analysis of statistic stratification on the severe complications of primary hepatocellular carcinoma

目的:通过分析原发性肝癌死亡病例,探讨合并各种并发症的分布规律及相关因素。方法:选取253份原发性肝癌死亡病例进行回顾性流行病学调查及相应分层分析。结果:原发性肝癌死亡病例中男、女患者性别比列为5∶1,其中死亡年龄男性患者偏低,女性患者在60岁以上;年龄因素与各并发症构成比有显著统计学意义,其中<40岁死亡病例中肝癌破裂出血所占比例较其他各组比例显著增高,而肝性脑病病例较其他各组病例数明显较低;40～49岁死亡病例中合并其他脏器转移的病例所占比例较其他病例较高;>80岁老年死亡病例中合并肝炎、肝硬化死亡病例明显较少,而肺部感染及呼吸衰竭病例较其他各组明显增高。结论:原发性肝癌死亡病例中各并发症构成与年龄、性别密切相关。

Objective： To investigate the distributing feature of the severe complications of primary hepatocellular carcinoma（HCC） as well as the relative factors in 253 died HCC cases. Methods： An analysis of statistic stratification was made in 253 died cases of primary hepatocellular carcinoma （HCC）, who were treated in our department, from 1999 to 2009. Results： The gender ratio was 5：1 between the male and the female in all 253 cases. The female age of death was significantly higher than the male ones. By the analysis of stratified statistics~ there was significant relation I^etween age of death and the constituent ratio of severe complication in 255 died HCC cases. The hemorrhage of HCC happened frequently in the cases less than 40 years old. On the contrary, the elder cases more than 80 years had the higher prevalence of lung infection as well as respiratory failure among the severe complications of HCC. Conclusion： The constituent ratio of the severe complication is closely related with the factor of gender and age in HCC death cases.