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磷酸肌酸钠治疗51例冠心病合并心力衰竭的疗效观察 被引量:8

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摘要 目的:探讨磷酸肌酸钠治疗冠心病合并心力衰竭的临床疗效和药物安全性。方法:随机将103例冠心病合并心力衰竭分为52例对照组和51例常规治疗联合磷酸肌酸钠的观察组,连续治疗1周为一疗程,3个疗程结束后对比临床疗效和药物安全性。结果:观察组总有效率94.12%优于对照组75.00%,P<0.01;组内治疗后血流动力学指标与治疗前比较,P<0.05;治疗组治疗后血流动力学指标与对照组比较,P<0.05;组间不良反应发生率比较,P>0.05。结论:在常规治疗的基础上联合磷酸肌酸钠能够明显改善冠心病合并心力衰竭患者的心肌能量代谢状态,不良反应发生率低,值得临床推广使用。
作者 王爱琴
出处 《中国医学创新》 CAS 2013年第3期130-131,共2页 Medical Innovation of China
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  • 1关天云,巫国勇,钟佛添,廖新学.磷酸肌酸治疗风心病慢性充血性心力衰竭的临床疗效观察[J].实用医学杂志,2005,21(7):741-742. 被引量:10
  • 2李彬.磷酸肌酸钠治疗充血性心力衰竭的临床观察[J].实用心脑肺血管病杂志,2006,14(7):556-557. 被引量:37
  • 3叶兴蓉,彭华生,王炜,孙海清,王晓湘.磷酸肌酸治疗老年慢性心力衰竭的临床观察[J].中国老年学杂志,2006,26(10):1410-1411. 被引量:44
  • 4Fedak PW. Paracdne effects of cel; transplantation: modifying ven- trieular remodeling in the failing hear [J]. Semin Thorae Cardiovasc Surg, 2008, 20(2): 87-93.
  • 5中华医学会心血管病分会.中华医学会心血管病杂志编委会,慢性心力衰竭诊断治疗指南.中华心血管病杂志,2007,:35-1098,1076.
  • 6Wallerson DC, Dereux RB. Reproducibilility of eehoeardiographic left ventricular measurements[J]. Hypertension, 1987,9(2) : 116.
  • 7Neubauer S, Krahe T, Sehindler R, et al. 31p magnetic resonance spectroscopy in dialted eardiomyopathy and coronary artery dis- ease Altered cardiac high - energy phosphate metabolism in heart faiure[J]. Circulation, 1992,86 : 1810.
  • 8Nagaya N,Kangawa K,Itoh T,et aI.Transplantation of mesenchymai stem cel Is improves cardiac function in a rat model of dilated cardiomyopathy[J], circ ulation, 2005, 112(8): 1128.
  • 9Werner L,Deutsch V,Barshackl,et aI.Transfer of endothelial progenit or c ells improves myoc cardiat performance in rats with dilated cardiomyopathy induc ed following experimental myocarditis[J].J Mol Cell Cardiol,2005, 39(4):691.
  • 10Komamura K,Tatsumi R,Miyazakf J,et al.Treatment of dilatedcardiomyo pathy with electro poration of hepatocyte growth factorgene into skeletal muscle[J]. Hypertension, 2004,44(3): 365.

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  • 1唐慧勤,王乃平,张玉萌.中药抗动脉粥样硬化作用机制的研究进展[J].中国药物应用与监测,2006,3(3):38-41. 被引量:8
  • 2卢永昕.慢性心力衰竭的临床评估和治疗原则——2005ACC/AHA慢性心力衰竭治疗指南简介[J].临床心血管病杂志,2005,21(11):691-695. 被引量:25
  • 3Balode I, Minte I, Latkovskis G, et al. Insufficient comrol of heart rate in stable coronary artery disease patients in Latvia[ J ]. Medici- ha(Kaunas) ,2014,50 (5) :295-302.
  • 4Elbarouni B, Cantor WJ, Ducas J, et al. Efficacy of an Early Inva- sive Strategy After Fibrinolysis in ST-Elevation Myocardial Infarc- tion Relative to the Extent of Coronary Artery Disease[ J]. Can J Cardiol,2014,30(12) : 1555-1561.
  • 5Perrone-Filardi P, Savarese G, Scarano M, et al. Prognostic impact of metabolic syndrome in patients with chronic heart failure : Data from GISSI-HF trial [ J]. Int J Cardio1,2014,23,178C :85-90.
  • 6Berthiaume JM,Young ME, Chert X, et al. Normalizing the meta- bolic phenotype after myocardial infarction : impact of subchronic high fat feeding[ J]. J Mol Cell Cardiol,2012,53 (1) :125-133.
  • 7Lygate CA, Bohl S,ten Hove M, et al. Moderate elevation of intra- cellular crcatine by targeting the creatine transporter protects mice from acute myocardial infarction[ J ]. Cardiovasc Res ,2012,1,96 (3) :466-475.
  • 8Xu Y, Jiang L, Huang Y, et al. Solid-state characterization and transformation of various creatine phosphate sodium hydrates [ J ]. J Pharm Sei ,2014,103 ( 11 ) :3688-3695.
  • 9张彬,赵宏.磷酸肌酸的心肌保护机制及其在心脏疾病中的应用[J].医学综述,2008,14(2):262-264. 被引量:73
  • 10臧修明.补阳还五汤治疗冠心病心绞痛48例临床观察[J].长春中医药大学学报,2009,25(5):701-702. 被引量:13

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