沉积物中雌激素及壬基酚、辛基酚、双酚A的测定

Analysis of Estrogens,Nonylphenol,4-tert-Octylphenol and Bisphenol A in the Sediments

近些年来雌激素及烷基酚类化合物由于其对水生生物的内分泌干扰作用越来越受到广泛关注.沉积物作为环境中有机污染物的重要储存库,研究目标物在其中的浓度分布对于探明此类物质在环境中的迁移转化具有重要意义.但沉积物中基质组成复杂而雌激素又痕量存在,这增加了前处理的难度.本研究从雌激素及烷基酚类化合物的理化性质入手,采用碱液提取、液液萃取和LC-MS/MS分析测定沉积物样品中的雌激素及壬基酚、辛基酚、双酚A.结果表明,经过优化的方法对7种目标物的回收率介于61.9%～93.7%之间.该方法能有效去除沉积物中那些不溶于强碱和既溶于酸又溶于碱的有机污染物,同时操作简单、成本低,但回收率高、检出限低,可广泛适用于河流沉积物样品及土壤样品的前处理.

Estrogens and alkylphenols have received much attention because of its endocrine disrupting effects to aquatic ecosystem in recent years. The fate of these compounds in sediments which is a repository of many organic pollutants has an important significance on the study of behaviors of target compounds in the environment. It is difficult to separate trace estrogens from sediments with complex matrices. Alkali extraction, liquid-liquid extraction and LC-MS/MS were used to analyze estrogens, nonylphenol, 4-tert-octylphenol and bisphenol A in sediments based on their physicochemical properties. The results showed that recoveries of the seven target compounds were 61.3%-93.7%. The established pretreatment method can effectively remove pollutants that cannot dissolve in alkali solution or that cannot dissolve in both acid and alkali solution. It can widely be used to analyze sediments and soil samples because of its low cost and simple operation but with high recoveries and low detection limit.