血清cTnI、CK-MB、Mb在急性心肌梗死诊断中的临床分析

目的分析血清cTnI、CK-MB、Mb在急性心肌梗死（AMI）诊断中的临床意义。方法选择AMI患者36例（观察组）与健康体检者30例（对照组），分析观察组血清cTnI、CK-MB、Mb水平的动态变化并与对照组进行比较，分析在AMI发病的不同时间段，观察组血清cTnI、CK-MB、Mb敏感性及特异性的动态变化。结果观察组发病6-12h、12-18h和18h-24h的cTnI、CK-MB、Mb动态检测结果与对照组相比，差异有统计学意义（20〈0．05，P〈0．01）；三项联合检测的敏感性均优于单一检查（P〈0．05或P〈0．01），且血清cTrd特异性最高。结论血清cTnI、CK．MB、Mb可作为AMI的早期诊断指标，动态检测可提示AMI的发生、发展；三项联合检测的敏感陛均优于单一检查的敏感眭，而特异眭以cTnI为高。

Objective To analyze the clinical significance of serum cTnI, CK-MB and Mb in the diagnosis of acute myocardial infarction. Method Collect 36 patients with acute myocardial infarction （ observation group ） and 30 healthy people （ control group ） , analyze the dynamic changes of serum cTnI, CK-MB and Mb levels in the observation group and compare with the control group, analyze the dynamic changes of sensitivity and specificity of serum cTnI, CK-MB and Mb levels in the observation group. Result There was a statistical significant （ P〈0.05, P〈0.01 ） in the serum cTnI, CK-MB and Mb in two groups in the incidence of6-12h, 12-18h and 18h-24; the sensitivity of combined detection was better than the sensitivity of single check （ P〈0.05, P〈0.01 ） , the specificity of serum cTnI was the highest in them.Conclusion Serum cTnI, CK- MB and Mb could be used as the indicator in the early diagnosis of AMI, the dynamic inspection results could prompted the occurrence and development ofAMI, the sensitivity of combined detection is significantly better than the sensitivity of the single check, the specificity of serum cTnI is the best in them.