单纯性肥胖症儿童血脂变化及其临床意义

Changes of blood lipid and clinical significance in simple obesity children

目的探讨单纯性肥胖症儿童血脂的变化及其临床意义。方法将117例单纯性肥胖症儿童设为肥胖组，120名正常体检健康儿童设为对照组，对两组的血清总胆固醇、三酰甘油、高密度脂蛋白及低密度脂蛋白水平进行测评分析。结果肥胖组血清总胆固醇、三酰甘油、低密度脂蛋白水平均显著高于对照组（P〈0．01），高密度脂蛋白水平与对照组比较差异无显著性（P〉0．05）。结论单纯性肥胖症儿童存在明显的脂质代谢紊乱，对心血管功能有潜在的危害，是成人罹患心血管疾病的危险因素，调节其血脂水平到正常范围，对预防成年后罹患心血管疾病具有重要意义。

Objective To explore the changes of blood lipid and clinical signifi- cance in simple obesity children. Methods A total of 117 simple obesity children were assigned to obesity group and 120 normal health examination ones to control group, levels of serum total cholesterol （TC）, triacylglycerol （TG）, HDL and LDL detected and analyzed for both groups. Results The levels of TC, TG and LDL were significantly higher in obesity then in control group （P〈0.01）, there was no significant difference in HDL （P〉0.05）. Conclusion Simple obesity children have obvious lipid metabolism disor- ders and potential harm in cardiovascular function, are risk factors of adults suffering from cardiovascular diseases, and regulating their blood lipid levels to normal limits has important significance for preventing adults from cardiovascular diseases.