摘要
喹诺酮类药物是一类广谱高效抗菌药物,广泛应用于畜禽和水产养殖。喹诺酮类药物在动物源食品中的残留会对人体健康造成危害。目前动物组织中喹诺酮类药物残留检测方法有很多,其中高效液相色谱(HPLC)和高效液相串联质谱法(HPLC-MS-MS)是主要方法。色谱法检测喹诺酮类药物的一般步骤为样品提取、净化、浓缩,进HPLC柱或HPLC-MS-MS柱定量检测。本文对色谱法检测动物源食品中喹诺酮类药物残留研究做简要综述,以期为食品中喹诺酮类的多残留检测提供一定的参考。
Quinolones is a kind of antibacterial agents with broad-spectrum antibacterial capability. It is widely applied in animal and aquaculture. The residues of quinolones in animal-derived foods can be dangerous for human health. HPLC (high performance liquid chromatography) and HPLC-MS-MS are major methods to analyze quinolones residues. The general steps of HPLC and HPLC-MS-MS for quinolones detection including sample extraction, purification, condensation and final quantitative detection have been reviewed in this paper.
出处
《食品科学》
EI
CAS
CSCD
北大核心
2013年第3期303-307,共5页
Food Science
基金
浙江省重点科技创新团队项目(2010R50028)
浙江省科技计划项目(20120F30021)