YKL-40在骨关节炎中的研究进展

Research Progress of YKL-40 in Osteoarthritis

国内外许多学者对能够及时反映关节软骨代谢状态的生物学标志物进行了大量研究,用以揭示其病情活动或预后。YKL-40是可反映软骨降解的生物学标志物之一,阐述YKL-40的来源、特性、检测方法以及诊断意义等,可使读者对此生物学标志物有一个全方面的认识以及对YKL-40与骨关节炎的密切关系有更为深刻的了解。

Many scholars have made a large number of studies for biological markers in order to better reflect the metabolic state of the articular cartilage and reveal the disease activity or prognosis.YKL-40 may be one of the biological markers of cartilage degradation.A full understanding of the biological marker and a deeper understanding of the close relationship between YKL-40 and osteoarthritis will be gained by elaborating YKL-40′s origin,characteristic,detection method,diagnostic significance and so on.