2009—2011年武汉大学人民医院门诊药房口服抗糖尿病药应用分析

Analysis of Utilization of Oral Antidiabetic Drugs in Outpatient Pharmacy of Wuhan University People's Hospital During 2009-2011

目的:了解2009—2011年我院门诊药房口服抗糖尿病药使用情况及变化趋势,为临床合理用药提供参考。方法:采用限定日剂量(DDD)法,对2009—2011年我院门诊药房口服抗糖尿病药的销售金额、用药频度(DDDs)及限定日费用(DDC)等指标进行统计、分析。结果:我院口服抗糖尿病药的销售金额和DDDs呈逐年上升趋势,其中α-葡萄糖苷酶抑制剂和双胍类药销售金额增幅明显,年均增长率分别为14.03%、21.14%,噻唑烷二酮类胰岛素增敏剂的销售金额呈下降趋势,年均增长率为-23.39%。结论:我院口服抗糖尿病药临床应用合理,双胍类药和α-葡萄糖苷酶抑制剂占主导地位,二肽基肽酶-4抑制剂增长较快,高效、安全、依从性好的药物受到临床青睐。

OBJECTIVE：To probe into the status quo and tendency of the utilization of oral antidiabetic drugs in the outpatient pharmacy of our hospital for reference of clinic rational administration of oral antidiabetic drugs.METHODS：By using the method of defined daily dose,the utilization of oral antidiabetic drugs in the outpatient pharmacy of our hospital during 2009-2011 was analyzed in respect of consumption sum,DDDs and DDC.RESULTS：The consumption sum and DDDs of oral antidiabetic drugs in our hospital increased year by year,much as in the consumption sum of α-glucosidase inhibitors and biguanides which witnessed an average annual growth rates of 14.03% and 21.14%,respectively;however,the consumption sum of thiazolidinedione showed a downward average annual growth rate of-23.39%.CONCLUSION：The utilization of oral antidiabetic agents in our hospital was rational on the whole with α-glucosidase inhibitors and biguanides topping the list.The use of Dipeptidyl peptidase 4 inhibitors increased sharply.The oral antidiabetic drugs with high performance,good safety and compliance are particularly welcome in the clinic.