摘要
目的:了解药品不良反应(ADR)发生的情况和危害,探讨ADR的防护措施,促进合理用药。方法:对我院2008年1月—2011年12月收集到的214例ADR报告,按ADR因果关系判断标准进行统计分析、评价。结果:214例ADR报告涉及药品127种,引起ADR例次最多的为抗感染药,共43种,其次为中药注射剂,共19种;累及器官和(或)系统以皮肤及附件损害最为常见,共108例次;其中5例为新的、严重的ADR。结论:ADR报告总数偏少。ADR的发生与多种因素有关,应增强合理用药意识,加强ADR报告意义的宣传,提高对ADR危害的认识,减少和避免严重的ADR发生,保证药物治疗安全、有效。
OBJECTIVE：To investigate the adverse drug reaction（ADR） and explore its hazard and prevention so as to promote rational drug use.METHODS： A total of 214 ADR cases collected in our hospital from Jan.2008 to Dec.2011 were statistically analyzed and evaluated using the evaluation criteria for ADR causality.RESULTS： A total of 127 drugs were involved in the 214 ADR cases,with anti-infective drugs topping the list（43 anti-infective drugs） in terms of number ADR cases,followed by traditional Chinese medicinal injections（19 traditional Chinese medicinal injections）.The ADR appeared mainly as lesions of skin and its appendants（108 cases）.5 ADR cases were new and serious ADR cases.CONCLUSION： The total number of ADR cases was on the low side.The ADR was associated with many factors.It is important to enhance consciousness on rational drug use,strengthen publicizing of the importance of ADR reporting and enhance cognition on the hazard of ADR so as to reduce and avoid the occurrence of serious ADR and ensure safe and effective medication.
出处
《中国医院用药评价与分析》
2013年第1期67-69,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
药品不良反应
分析
合理用药
Adverse drug reactions（ADR）
Analysis
Rational drug use
