间隙蓝光照射治疗新生儿黄疸的可行性分析

Feasibility of intermittent blue light irradiation in the treatment of neonatal jaundice.

目的比较间隙和持续性光疗治疗新生儿黄疸的临床疗效。方法按纳入标准选择新生儿黄疸100例,随机分为治疗组和对照组,治疗组患儿实施间隙蓝光照射,对照组实施持续蓝光照射,比较两组患儿的治疗效果。结果治疗组有效率为95.8%,对照组有效率为91.3%,差异无统计学意义(P>0.05)。与对照组比较,治疗组治疗后的胆红素下降幅度更大,差异有统计学意义(P<0.05);不良反应发生率低,尤其是皮疹和发热发生率,差异有统计学意义(P<0.05)。结论间隙蓝光照射治疗是可靠的、有效的方法,比持续蓝光照射治疗更具临床优势。

Objective To explore the clinical efficacy of intermittent blue light irradiation and continuous in-termittent blue light irradiation in the treatment of neonatal jaundice. Methods One hundred patients with neonatal jaundice were divided into the study group and the control group. Patients in the study group were treated with intermit-tent blue light irradiation, while those in the control group were treated with continuous intermittent blue light irradia- tion. The clinical efficacy was compared between the two groups. Results The effective rate was 96.0% in the study group and 90.0% in the control group, with statistically significant difference between the two groups. Compared with the control group, the study group had significantly decreased levels of bilirubin （P〈0.05） and lower incidence of ad-verse reactions （especially rash and fever, P〈0.05）. Conclusion Intermittent blue ray irradiation is reliable and effec-tive for treating neonatal jaundice, which has more clinical advantages over continuous blue light irradiation.