多重耐药鲍曼不动杆菌的耐药机制及防治策略

Resistance Mechanism and Control Strategy of Multi-Resistant Acinetobacter Baumannii

鲍曼不动杆菌是一类条件致病菌,广泛分布于自然界中。随着抗菌药物的广泛使用,鲍曼不动杆菌对抗菌药物的耐药逐年上升,己成为院内感染的重要菌株,常可引起肺炎、尿道感染、脑膜炎、菌血症等各种难治性感染。了解其耐药机制,探讨克服耐药的方法,对于临床上治疗和预防其引起的感染有重大的意义。

Acinetobacter baumannii is a kind of opportunistic pathogenic bacteria,which is widely distributed in nature.With the wide spread use of antibacterial drugs,antibiotic resistance in Acinetobacter baumannii is rising year by year.Acinetobacter baumannii has become an important pathogen in the nosocomial infections,which can result in various refractory infections such as： pneumonia,urinary tract infection,meningococcal and bacteremia etc.Understanding the resistance mechanism,explore ways to overcome drug resistance,is very important to clinical treatment and prophylaxis of other infections caused by Acinetobacter baumannii.