局麻下甲状腺腺瘤切除术右美托咪啶应用的临床观察

Clinical Observation of Dexmedetomidine for Thyroid Adenoma Resection Patients under Local Anesthesia

目的探究在甲状腺腺瘤患者局麻下加用右美托咪定的临床疗效。方法截取我院2009年3月至2012年1月共100例甲状腺腺瘤患者,按随机数字表分为实验组及对照组各50例,实验组局麻下加用右美托咪定干预,对照组为局麻下予生理盐水安慰剂干预,对比两组患者间临床资料差异性。结果实验组较对照组镇静效果好,利多卡因用量少,住院时间短,血压、心率波动幅度小。结论右美托咪定在局麻甲状腺腺瘤切除术患者中应用镇静安全,易唤醒,无呼吸抑制,并减少局麻药量,效果理想。

Objective To explore the clinical efficacy of thyroid adenoma patients under local anesthesia with dexmedetomidine. Methods 100 cases of thyroid adenoma patients in our hospital from March 2009 to January 2012 were chosen and randomly divided into the experimental group and the control group with 50 cases in each group. The patients under local anesthesia were intervened with dexmedetomidine in the experimental group, while the patients under local anesthesia were intervened with saline placebo in the control group. The clinical data differences between the two groups＇ patients were compared. Results The sedative effect in the experimental group was better than that in the control group. As for the experimental group, the dosage of lidocaine was larger, the hospitalization time was shorter, and blood pressure and heart rate fluctuation amplitude was smaller. Conclusion Dexmedetomidine was safe for the excision of thyroid adenoma patients under local anesthesia. It was easy to waken patients and no respiratory depression was found. It could also reduce the amount of local anesthetics. All in all, the effect was ideal.