银杏达莫联合腺苷钴胺治疗糖尿病周围神经病变临床观察

Clinical observation of “Ginkgo Leaf Extract and Dipyridamole Injection” with cobamamide in treating diabetic peripheral neuropathy

目的观察银杏达莫联合腺苷钴胺治疗糖尿病周围神经病变的临床疗效。方法将62例糖尿病周围神经病变患者随机分为治疗组、对照组,各31例;治疗组给予银杏达莫联合腺苷钴胺治疗,对照组单用腺苷钴胺治疗。两组疗程均为20天,观察周围神经传导速度变化情况,并评价临床疗效。结果治疗组、对照组总有效率分别为87.1%、58.1%;组间临床疗效比较,差异有统计学意义(P<0.05)。治疗前后组内比较,两组正中神经、尺神经、腓总神经的运动神经及正中神经、尺神经、腓浅神经的感觉神经传导速度差异均有统计学意义(P<0.05,P<0.01);组间治疗后比较,各指标差异均有统计学意义(P<0.05)。结论银杏达莫联合腺苷钴胺治疗糖尿病周围神经病变疗效良好。

Objective To observe the therapeutic effect of ＂ Ginkgo Leaf Extract and Dipyridamole Injection＂ with cobamamide in treating diabetic peripheral neuropathy. Methods Sixty-two subjects were randomized into two groups： treatment group in which 31 cases were treated by ＂ Ginkgo Leaf Extract and Dipyridamole Injection＂ with cobamamide, and control group in which 31 cases were treated by eobamamide,with the course of 20 days. The nerve conduction velocity and the clinical efficacy were observed after treatment. Results The total effective rate was 87.1% in the treatment group and 58.1% in the control group,with a significant difference between them （ P 〈 0.05 ） . After treatment, the nerve conduction velocity of both groups were improved （ P 〈 0.05 ）, but the improvement in the treatment group was superior to that in the control group （ P 〈 0.05 ）. Conclusion ＂Ginkgo Leaf Extract and Dipyridamole Injection＂ with cobamamide has positive effects on diabetic peripheral neuropathy.