医务人员鼻前庭带菌情况及细菌耐药性研究

RESEARCH ON THE MEDICAL PERSONNEL NASAL VESTIBULE CONTAMINATION AND DRUG RESISTANCE OF THE BACTERIA

目的研究临床医护人员鼻前庭带菌情况及其耐药性,为制定有效控制措施提供依据。方法采用现场采样和细菌分离鉴定方法,对天津市部分不同级别医疗机构重点科室医务人员进行了调查。结果现场采集鼻前庭标本945份,共分离到革兰阴性菌332株,分离率为35.13%。鼻前庭检出的革兰阴性菌对临床常用抗菌药物耐药率比较高,总平均耐药率为39.46%;其中多重耐药菌株占25.30%,敏感菌株占46.99%。结论天津市医疗机构临床医务人员鼻前庭革兰阴性菌携带率较高,且普遍耐药,应当加强医务人员自身带菌情况监测和控制措施。

Objective To study bacteria carrying status of the clinical staff in nasal vestibule and the drug resistance, and provide basis for making control measures. Methods Field sampling and bacterial isolation and identification were used to investigate the condition of natural carrier of medical staff in key departments of hospitals in Tianjin. Results 945 nasal samples of medical staff were collected. 332 Gram- negative bacteria were isolated, the isolation rate was 35.13%. The Gram - negative bacteria detected in nasal vestibule were highly resistant to commonly used antimicrobial drugs, the to- tal average resistance rate was 39.46% ; of them the multi - drug resistant strains accounted for 25.30%, the sensitive strains accounted for 46.99%. Conclusion In the nasal vestibule of the clinical staff of medical institutions in Tianjin, Gram- negative bacteria carrier rate is high, with generally drug resistance. Medical staff contamination monitoring and control measures should be strengthened.