大承气汤包装袋安全性研究

Safety of packaging pouch of Dachengqi Decoction

目的对大承气汤包装袋进行安全性研究。方法从煎液本身性质,如煎液的稳定性、pH值、灰分、重金属、有效成分等方面,对煎液予以考察,并且对包装袋吸附煎液有效成分、吸附量及包装袋残留物予以检测,采用高效液相色谱法、气相色谱法对中药汤剂包装袋予以分析。结果大承气汤经过10d低温及常温存放,汤剂性质稳定,产生沉淀较少,且pH值、灰分、重金属、有效成分均没有很大的变化,包装袋对煎液吸附量较少,对煎液有效成分不会产生很大影响,包装袋经过高温之后不会产生有害成分,且本身性质稳定,从不同角度予以分析,可以用于大承气汤包装。结论通过对大承气汤包装袋予以分析,为中药煎液包装袋安全性研究提供依据。

Objective To study the safety of Dachengqi Decoction packaging pouches made by liquid medicine packaging composite membrane.Methods The decoction properties,such as decoction stability,pH value,ash content,heavy metal,and effective components,were investigated,and the effective components,adsorption content,and residues in the adsorption decoction in pouches were inspected using high performance liquid chromatography and gas chromatography.Results After 10 d stored at low and normal temperature,Dachengqi Decoction was stable in property with no significant change in pH value,ash content,heavy metal,and effective components,and produced less precipitation.With the less adsorption content of the decoction,the packaging pouches could hardly have any influence on the effective components in the decoction and they produced no harmful components after being treated with high temperature.Because of the stability of packaging pouches,they could be used for the packaging of Dachengqi Decoction.Conclusion The packaging pouches of Dachengqi Decoction are analysed,in the study which could provide the theoretical basis for the packaging pouches of decoction.