锐孔法制备黄酮类化合物微胶囊及其释放性的研究

Microencapsulation of Flavonoids Compounds by Piercing Method and their Release in vitro

以海藻酸钠为壁材,采用锐孔法制备黄酮类化合物微胶囊。通过单因素和正交试验确定影响黄酮类化合物微胶囊制备的主要因素,优化工艺条件。实验确定最佳优化工艺条件为:海藻酸钠浓度为1.4%,芯壁比为3:2,CaCl2浓度为1.4%,单甘酯/芯材为0.2g/g,在此条件下,产品的平均包埋率可达92.59%,且微胶囊产品结构坚硬、圆整,无拖尾现象。

Microcapsules containing flavonoids compounds were prepared by piercing method with sodium alginate as shell material. Through the single factor and orthogonal test to determine flavonoids microcapsule preparation influence of the main factors. The best technological conditions were sodium alginate concentration of 1.4%, core/wall material ratio of 1：1, CaC12 concentration of 1.4%, and monoglyceride/core ratio of 0.2 g/g. Under these conditions, encapsulation efficiency reached 92.59%.Microcapsule products structure was hard and round with no trailing phenomenon.