2Romas E, Gillespie MT, Martin TJ. Involvement of receptor acti- vator of NFkappaB ligand and tumor necrosis factor-alpha in bone destruction in rheumatoid arthritis. Bone, 2002, 30: 340- 346.
3Lacey DL, Timms E, Tan HL, et al. Osteoprotegerin ligand is a cytokine that regulates osteoelast differentiation and activation. Cell, 1998, 93: 165-176.
4Anderson DM, Maraskovsky E, Billingsley WL, et al. A homo- logue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. Nature, 1997, 390: 175-179.
5Kong YY, Feige U, Sarosi I, et al Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteo- protegerin ligand. Nature, 1999, 402: 304-309.
6Sakata M, Shiba H, Komatsuzawa H, et al. Expression of osteo- protegerin (osteoclastogenesis inhibitory factor) in cultures of hu- man dental mesenchymal cells and epithelial cells. J Bone Miner Res, 1999, 14: 1486-1492.
7~idal NO, Brandstrom H, Jonsson KB, et al. Osteoprotegerin mRNA is expressed in primary human osteoblast-like cells: down-regulation by glucocorticoids. J Endocrinol, 1998, 159: 191-195.
8Collin-Osdoby P, Rothe L, Anderson F, et al. Receptor activa- tor of NF-kappa B and osteoprotegerin expression by human mi- crovascular endothelial ceils, regulation by inflammatory cy- toklnes, and role in human osteoclastogenesis. J Biol Chem, 2001, 276: 20659-20672.
9Mitani M, Miura Y, Saura R, et al. Estrogen specifically stimu- lates expression and production of osteoprotegerin from rheuma- toid synovial fibroblasts. Int J Mol Med, 2005, 15: 827-832.
10Zannettino AC, Holding CA, Diamond P, et al. Osteoprotegerin (OPG) is localized to the Weibel-Palade bodies of human vascu- lar endothelial cells and is physically associated with von WiUe- brand factor. J Cell Physiol, 2005, 204: 714-723.
