微晶纤维素的合成

The Synthesis of Microcrystalline Cellulose

作为天然植物纤维原料制品，微晶纤维索在医药食晶工业中具有先天的优势和独特的性质，是多功能的辅料[1]。国外微晶纤维素产品主要是以特殊等级的商α-纤维素含精的纯水材纤维素为原料，而国内传统采用棉为原料，其中棉短绒中纤维索含量较高，约在90％以上，是制备微晶纤维素的良好原料[2]。本实验主要探讨由棉短绒制备微晶纤维素的条件。实验发现脱脂过程中氢氧化钠浓度和脱脂时间有较大影响，最佳条件为20％氢氧化钠溶液室温下浸泡72h．然后在90～95℃水浴温度下搅拌约220min。脱脂后的棉短绒经过氧化氢漂白后直接用盐酸催化水解．水解过程中盐酸浓度、时间和温度对最终产物影响较大，结晶最好的条件为10％盐酸、90℃搅拌水解145min。测试了产物的XRD，证明所得的产物有较好的结晶度。

As products from natural plant fiber, microcrystalline cellulose has congenital advantages and unique properties in medicine and food industry. It is a multi-functional accesssories. In the foreign country, the high content of or-cellulose of pure wood fiber can be the raw material. But in China, cotton is always used to produce microcrystalline cellulose. And cotton linters is the better, because of it＇s content of cellulose is quite high（about 90 %）. This experiment mainly discussed the conditions of the synthesis of microcrystalline cellulose. It was find that, the concentration of sodium hydroxide, the time of heating all c-an influence the quality of the product. Soaking lbr 72 h with sodium hydroxide at room temperature, of which the concentration was 20 %, then stirring for 220 min at 90-95 ℃ can be the best condition. Moreover, the concentration of hydrochloric acid, the time and the temperature of hydrolysis will affect the molecular weight of the final product. Stirring for 145 min at 90 ℃ with hydrochloric acid, of which the concentration was 10 %. The crystal linity of it was well through XRD.