炎琥宁联合异丙嗪治疗毛细支气管炎90例疗效观察

An observation of the effect of potassium sodium pehydroandroandrographolide succinate and promethazine on 90 cases of pediatric acute bronchiolitis

目的:观察炎琥宁联合异丙嗪治疗毛细支气管炎的疗效。方法:将180例毛细支气管炎患儿随机分为2组,对照组90例给予利巴韦林、二羟丙茶碱静脉滴注,治疗组在此治疗基础上加用炎琥宁静脉滴注、异丙嗪肌注,疗程5～7 d。结果:治疗组在咳喘及肺部喘鸣音消失、痊愈时间方面均优于对照组,差异有高度统计意义(P<0.01)。治疗组总有效率为97.8%,对照组总有效率为88.9%,2组比较差异有统计意义(P<0.05)。结论:炎琥宁联合异丙嗪治疗毛细支气管炎疗效确切,未见明显不良反应。

Objective： To observe the effect of potassium sodium pehydroandroandrographolide succinate combined with promethazine on pediatric acute bronchiolitis. Methods： 180 children with acute bronchiolitis were randomly and evenly divided into two groups control group （90 cases ） treated with ribavirin and diprophylling for a course of 5 -7 days; treatment group （90 cases） were treated with ribavirin, diprophylling plus intravenous infusion of potassium sodium pehydroandroandrographolide suits： The treatment group was superior to the control cough and asthmatoid noise in lung and the differences succinate and promethazine for a course of 5 -7 days. Regroup at the remission in dyspnoea and the disappearance of was statically significant （ P〈0.01 ）. The total effective rate was 97.8% in treatment group and 88.9% in control group respectively. There was a significant difference between the two groups （P〈0.05）. Conclusion： The using of potassium sodium pehydroandroandrographolide succinate and promethazine is effective and safe without obvious side effect in treating children with acute bronchiolitis.