益肾化浊通络方治疗慢性肾炎肾衰97例临床观察

Clinical Observation of Yishen Huazhuo Tongluo Prescription in Treating 97 Cases of Renal Failure Due to Chronic Nephritis

目的:观察益肾化浊通络方治疗慢性肾炎导致的慢性肾功能衰竭的疗效。方法:将97例患者以口服益肾化浊通络方治疗,观察在对慢性肾功能衰竭治疗过程中肌酐、尿酸、尿素氮、尿蛋白、尿隐血等的变化。4w为1个疗程。结果:2个疗程后,总有效率为88.66%。治疗前治疗后肌酐、尿素氮、尿酸、尿蛋白、尿隐血,差异均有统计学意义(P<0.01)。尿酸与肌酐、尿素氮存在正相关关系(P<0.01)。治疗前、治疗后,症状及体征改善,差异有统计学意义(P<0.01)。结论:益肾化浊通络方在治疗慢性肾炎导致的慢性肾功能衰竭过程中,降低肌酐、尿酸、尿素氮、尿蛋白、尿隐血均有显著地疗效,而且治疗慢性肾功能衰竭第1、第2、第3、第4期均有显著的疗效,对于症状的改善也具有显著的疗效。

Objective： To observe the effect of Yishen Huazhuo TongLuo prescription in treating chronic renal failure due to chronic ne- phritis. Methods： A total of 97 patients were treated with oral Tongluo kidney detoxification, and creatinine, uric acid, Urea nitrogen, u- rine protein, urine occult blood and other changes were observed. 4 weeks for a course of treatment. Results： Two months after treat- ment, the total effective rate was 88.66%. Before and after treatment, the differences in creatinine, urea nitrogen, uric acid, urine pro- tein, urine occult blood, were significant （P 〈0. 01 ）. Uric acid and creatinine, urea nitrogen are positively correlated （P 〈0. 01 ）. Before and after treatment, the differeance in improvement of symptoms and signs was significant （ P 〈 0. 01 ）. Conclusion： Yishen Hua- zhuo TongLuo prescription can significantly reduce creatinine, uric acid, urea nitrogen, urine protein, urine occult blood in patients with chronic renal failure. During phase 1, 2, 3, 4 of the disease, it showed a significant effect, and significantly improved the symptoms.