酶反应提取技术在中药化学成分提取中的应用

Application Progress on Enzymatic Extraction Technology in Extraction of Chemical Compositions of Chinese Medicine

酶反应提取技术(生物酶解提取技术)是利用酶反应所具有高度专一性的特点,通过适当的酶选择性地破坏植物细胞壁,使植物细胞内的成分更容易溶解、扩散的原理而应用于中药有效成分提取的新技术。该技术不但具有条件温和、易除杂质、节约能耗、浸出率高、设备简易、减少热敏成分降解等优势,而且具有应用于大规模工业化生产的潜力。其应用前景十分广阔,已经广泛用于中药多糖类、生物碱类、黄酮类、皂苷类、蛋白质类、有机酸类等成分的提取。我们就该技术的应用进展及方法特点做一系统性概述,以期新技术能够更加合理而有效的应用于中药化学成分的提取。

Enzymatic extraction technology is based on the highly specific feature of enzyme, which is used to destroy the plant cell wall selectively, making active components inside plant cell more easily to dissolve and spread. Based on the above principle, this new tech- nique is being broadly used in the aspects of TCMs extraction. This technology not only has the advantage of mild conditions,removing impurity easily, saving energy consumption ,ratio high leaching, simple equipment and reducing degradation of thermal ingredient, but also has the potential of large - scale industrial production. It has been widely used in the extraction of chemical compositions of Chinese med- icine,including polysaccharides,alkaloids,flavonoids,saponins,proteins,organic acids, et al. This article has made a systematic exposi- tion to this technology＇ s application progress and method characteristics, so as to make new technology can be more reasonable and effec- tive in active components＇ extraction of Chinese Materia Medica.