摘要
目的探讨移居高原低氧环境6个月后男性精子中CatSperlmRNA表达水平与精子活力之间的相关性及意义。方法分别收集27例海拔1500m健康男性及其移居高原6个月后的精液标本行精液质量分析检测男性精液质量，SYBRGreen实时定量PCR检测精子CatSperlmRNA的表达水平。结果移居高原低氧环境6个月后男性精液质量不同程度的下降（P〈0．05）；且精子活力与精子中CatSperlmRNA表达水平呈正相关（P〈0．05）。结论移居高原低氧环境6个月后男性精子活力下降，可能与高原低氧环境下影响男性精子中CatSperlmRNA水平及其表达相关。
Objective To investigate the expression of CatSperl mRNA and its significance in spermatozoa or healthy males living in high altitude about 6 months. Methods The semen specimens of 27 healthy male living in Plain were collected, and the semen specimens were accordingly collected after they move to high altitude area and lived there about 6 months. The expression of CatSperl mRNA was detected by SYBR Green RT-PCR. Results Male sperm quality and the expression of CatSperl mRNA were all declined under living in high altitude area （P〈0.05）; The expression of CatSperl mRNA was positively correlated with sperm motility （P〈0.05）. Conclusion The expression level of CatSperl mRNA might positively correlate with sperm motility.
出处
《中国男科学杂志》
CAS
CSCD
北大核心
2012年第12期27-29,38,共4页
Chinese Journal of Andrology
基金
兰州军区医疗卫生科研基金（CLZ11JB09）
