期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

1，25-二羟维生素D3对支气管哮喘小鼠气道重塑的影响及其机制 被引量：11

原文传递
导出
摘要 1，25-二羟维生素D3[1，25-dihydroxyvitaminD3，1，25-（OH）2D3]是体内维生素D最重要的活性代谢产物。既往研究均侧重于1，25-（OH）2D3调控支气管哮喘（简称哮喘）免疫应答及慢性气道炎症反应^[1-2]。
作者 宋颖芳 赖国祥 柳德灵 林庆安 郑曦 林海
机构地区 厦门大学附属东方医院南京军区福州总医院呼吸与危重症医学科
出处 《中华结核和呼吸杂志》 CAS CSCD 北大核心 2013年第2期119-121,共3页 Chinese Journal of Tuberculosis and Respiratory Diseases
基金 国家自然科学基金（81100011）
关键词 25-二羟维生素D3 支气管哮喘 哮喘小鼠 气道重塑 25-(OH)2D3 活性代谢产物 气道炎症反应 免疫应答
分类号 R562.25 [医药卫生—呼吸系统]
  • 相关文献

参考文献13

  • 1Taher YA, van Esch BC, Hofman GA, et al. 1 alpha, 25-dihydroxyvitamin D3 potentiates the beneficial effects of allergenimmunotherapy in a mouse model of allergic asthma : role for IL-10and TGF-beta J Immunol, 2008, 180 : 5211-5221.
  • 2Gorman S, Judge MA, Burchell JT, et al. 1,25-dihydroxyvitaminD3 enhances the ability of transferred CD4 + CD25 + cells tomodulate T helper type 2-driven asthmatic responses.Immunology, 2010,130:181-192.
  • 3揭志军,金美玲,蔡映云,袁正宏,胡芸文,徐扬,任涛,杨振华.胞嘧啶-磷酸-鸟嘌呤寡脱氧核苷酸对慢性支气管哮喘小鼠气道重塑的影响[J].中华结核和呼吸杂志,2006,29(9):612-616. 被引量：7
  • 4Matheu V, Back 0,Mondoc E, et al. Dual effects of vitamin D-induced alteration of TH1/TH2 cytokine expression : enhancingIgE production and decreasing airway eosinophilia in murineallergic airway disease. J Allergy Clin Immunol, 2003,112:585-592.
  • 5Girodet PO,Ozier A,Bara I,et al. Airway remodeling in asthma:new mechanisms and potential for pharmacological intervention.Pharmacology Ther, 2011,130 : 325-337.
  • 6Gupta A, Sjoukes A, Richards D, et al. Relationship betweenserum Vitamin D,disease severity,and airway remodeling inchildren with asthma. Am J Respir Crit Care Med, 2011,184:1342-1349.
  • 7Zosky GR, Berry U, Elliot JG, et al. Vitamin D deficiencycauses deficits in lung function and alters lung structure. Am JRespir Crit Care Med, 2011,183 : 1336-1243.
  • 8Janjetovic Z,Brozyna AA, Tuckey RC, et al. High basal NF-kBactivity in nonpigmented melanoma cells is associated with anenhanced sensitivity to vitamin D3 derivatives. Br J Cancer,2011,105:1874-1884.
  • 9Kwon HJ, Won YS, Nam KT,et al. Vitamin D3 upregulatedprotein 1 deficiency promotes N-methyl-N-nitrosourea andHelicobacter pylori-induced gastric carcinogenesis in mice. Gut,2012, 61:53-63.
  • 10Tachi K,Takami M, Zhao B,et al. Bone morphogenetic protein 2enhances mouse osteoclast differentiation via increased levels ofreceptor activator of NF-kB ligand expression in osteoblasts. CellTissue Res, 2010,342:213-220.

二级参考文献9

  • 1Temelkovski J,Hogan SP,Shepherd DP,et al.An improved murine model of asthma:selective airway inflammation,epithelial lesions and increased methacholine responsiveness following chronic exposure to aerosolised allergen.Thorax,1998,53:849-856.
  • 2Tomasek JJ,Gabbiani G,Hinz B,et al.Myofibroblasts and mechano-regulation of connective tissue remodelling.Nat Rev Mol Cell Biol,2002,3:349-363.
  • 3Vignola AM,Chanez P,Chiappara G,et al.Transforming growth factor-beta expression in mucosal biopsies in asthma and chronic bronchitis.Am J Respir Crit Care Med,1997,156 (2 Pt 1):591-599.
  • 4Banerjee B,Kelly KJ,Fink JN,et al.Modulation of airway inflammation by immunostimulatory CpG oligodeoxynucleotides in a murine model of allergic aspergillosis.Infect Immun,2004,72:6087-6094.
  • 5Kitagaki K,Jain VV,Businga TR,et al.Immunomodulatory effects of CpG oligodeoxynucleotides on established th2 responses.Clin Diagn Lab Immunol,2002,9:1260-1269.
  • 6Kline JN,Kitagaki K,Businga TR,et al.Treatment of established asthma in a murine model using CpG oligodeoxynucleotides.Am J Physiol Lung Cell Mol Physiol,2002,283:L170-L179.
  • 7Takabayashi K,Libet L,Chisholm D,et al.Intranasal immunotherapy is more effective than intradermal immunotherapy for the induction of airway allergen tolerance in Th2-sensitized mice.J Immunol,2003,170:3898-3905.
  • 8金美玲,蔡映云,袁正宏,郑玲洁,任涛.免疫刺激DNA序列与过敏原联用对哮喘小鼠模型气道过敏性炎症的作用[J].中华结核和呼吸杂志,2002,25(9):542-545. 被引量：3
  • 9金美玲,蔡映云,袁正宏,郑玲洁,张伟.CpGDNA预防小鼠哮喘模型的形成[J].复旦学报（医学版）,2002,29(5):376-378. 被引量：10

共引文献6

同被引文献140

  • 1祁晓平,黎介寿.1,25-二羟维生素D3的免疫调节作用[J].肠外与肠内营养,2006,13(2):105-108. 被引量：14
  • 2Persson Louise Jeanette Pauline,Aanerud Marianne,Hiemstra Pieter Sicco,Hardie Jon Andrew,Bakke Per Sigvald,Eagan Tomas Mikal Lind.Chronic obstructive pulmonary disease is associated with low levels of vitamin d. PloS one . 2012
  • 3Mansbach JM, Ginde AA, Camargo CA Jr. Serum 25-hydroxyvitamin D levels among US children aged 1 to 11 years : dochildren need more vitamin D. [ J]. Pediatrics, 2009, 124(5):1404-1410.
  • 4Camargo CA Jr, Rifas-Shiman SL, Litonjua AA, et al. Maternalintake of vitamin D during pregnancy and risk of recurrent wheezein children at 3 y of age[ J]. Am J Clin Nutr,2007,85(3) :788-795.
  • 5Hollams EM, Hart PH, Holt BJ, et al. Vitamin D and atopy andasthma phenotypes in children : a longitudinal cohort study [ J ].Eur Respir J, 2011,38(6):1320-1327.
  • 6Gale CR, Robinson SM, Harvey NC, et al. Maternal vitamin Dstatus during pregnancy and child outcomes[ J]. Eur J Clin Nutr,2008,62(1) :68-77.
  • 7Chinellato I,Piazza M, Sandri M, et al. Vitamin D serum levelsand markers of asthma control in Italian children [ J ]. J Pediatr,2011,158(3) : 437 441.
  • 8Brehm JM, Celed6n JC, Soto-Quiros ME, et al. Serum vitamin Dlevels and markers of severity of childhood asthma in Costa Rica[J] . Am J Respiv Crit Care Med, 2009,179(9) : 765-771.
  • 9Brehm JM, Schuemann B, Fuhlbrigge AL, et al. Serum vitaminD levels and severe asthma exacerbations in the Childhood AsthmaManagement Program study [ J ]. J Allergy Clin Immunol, 2010,126(1) : 52-58.
  • 10Majak P, Olszowiec-Chlebna M, Smejda K, et al. Vitamin Dsupplementation in children may prevent asthma exacerbationtriggered by acute respiratory infection [ J ]. J Allergy ClinImmunol, 2011, 127(5) : 1294-1296.

引证文献11

二级引证文献163

中华结核和呼吸杂志
2013年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部