活性维生素D3对白蛋白诱导人肾小管上皮细胞转分化的影响
被引量：1
摘要
肾小管上皮细胞转分化（EMT）是目前公认的导致肾间质纤维化（RIF）的主要原因，其主要标志有钙黏蛋白间质纤维（RIF）的主要原因，其主要标志有钙黏蛋白（E-cadherin）表达下调，α平滑肌肌动蛋白（α-SMA）表达上调，产生纤连蛋白（FN）等细胞外基质（ECM）成分。
出处
《中华肾脏病杂志》
CAS
CSCD
北大核心
2013年第2期147-149,共3页
Chinese Journal of Nephrology
参考文献5
-
1Kalluri R,Weinberg RA. The basics of epithelial-mesenchymal transition[J].Journal of Clinical Investigation,2009.1420-1428.
-
2Zhao J,Alfonso TS,Paul M. Albumin-stimulated TGFbeta1 in renal tubular cells is associated with activation of MAPkinase[J].International Urology and Nephrology,2007.1265-1271.
-
3Li Y J,Tan XY,Dai CS. Inhibition of integrin-linked kinase attenuates renal interstitial fibrosis[J].Journal of the American Society of Nephrology,2009.1907-1918.
-
4Tian J,Liu Y,Williams LA. Potential role of active vitamin D in retarding the progression of chronic kidney disease[J].Nephrology Dialysis Transplantation,2007.321-328.
-
5李晓东,丁新国,高山林,郭志军,李英.1，25（OH）2D3对甲状旁腺激素诱导的肾小管上皮细胞转分化和转化生长因子β1表达的影响[J].中华肾脏病杂志,2010,26(3):227-228. 被引量：2
二级参考文献4
-
1Tan X,Li Y,Liu Y.Therapeutic role and potential mechanisms of active Vitamin D in tenal interstitial fibrosis.J Steroid Biochem Mol Biol,2007,103:491-496.
-
2Li Y,Spataro BC,Yang J,et al.1,25-dihydroxyvitamin D inhibits renal interstitial myofibroblast activation by inducing hepatocyte growth factor expression.Kidney Int,2005,68:1500-1510.
-
3郭云珊,袁伟杰,叶菡洋,傅鹏,梅小斌,战晓丽,刘凌.甲状旁腺激素对人近曲小管上皮细胞转分化及分泌结缔组织生长因子的影响[J].中华肾脏病杂志,2008,24(5):332-336. 被引量：7
-
4李晓东,丁新国,李英.甲状旁腺素对人肾小管上皮细胞转分化和TGF-β1表达的影响[J].细胞与分子免疫学杂志,2009,25(1):73-74. 被引量：6
同被引文献15
-
1Lydia A, Asanuma K, Nonaka K, et al. Effects of 22-oxa- calcitriol on podocyte injury in adriamycin-induced nephrosis[J]. Am J Nephroh 2012,35(1 ) : 58-68.
-
2Song Z, Guo Y, Zhou M, et al. The PI3K/p-Akt signaling pathway participates in calcitriol ameliorating podocyte injury in DN rats[J].Metabolism, 2014,63(10) : 1324- 1333.
-
3Nakai K, Fujii H, Kono K, et al. Vitamin D activates the Nrf2-Keapl antioxidant pathway and ameliorates nephropathy in diabetic rats[J]. Am J Hypertens, 2014,27 (4) : 586-595.
-
4Perez-Gomez MV, OrtiArduan A, Lorenzo-Sellares V. Vitamin D and proteinuria: a critical review of molecular bases and clinical experience [J]. Nefrologia, 2013,33 (5) : 716-726.
-
5Radford MJ, Donadio J.l, Bergstralh EJ, et al. Predicting renal outcome in IgA nephropathy[J]. J Am SOc Nephrol, 1997,8(2) : 199-207.
-
6Wu-Wong JR, Chen YW, Wessale JL. Vitamin D receptor agonist VS-105 improves cardiac function in the presence of enalapril in 5/6 nephrectomized rats[J]. Am J Physiol Renal Physiol, 2015,308(4) :F309-F319.
-
7Yang WS, Kim HW, Lee JM, et al. 1,25 dihydroxy vitamin 133 causes ADAM10-dependent ectodomain shedding of tumor necrosis factor receptor 1 in vascular smooth muscle cells[J]. Mol Pharmacol, 2015,87(3) :533-542.
-
8Wu HJ, Lo Y, Luk D, et al. Alternatively activated dendritic cells derived from systemic lupus erythematosus patients have tolerogenic phenotype and function [J]. Clin Immunol, 2(115,156(1) :43-57.
-
9Thangamani S, Kim M, Son Y, et al. Cutting edge: progesterone directly upregulates vitamin d receptor gene expression for efficient regulation of T cells by calcitriol[J]. J Immunol, 2015,194(3) : 883-886.
-
10Liu Y. Epithelial to mesenchymal transition in renal fibrogenesis: pathologic significance, molecular mechanism, and therapeutic intervention[J]. J Am Soc Nephrol, 2004,15 (1) : 1 - 12.
二级引证文献6
-
1张阳阳,郭一沙,陈孝储,吴阳,俞昶乐,张莉.优化积雪草苷非离子表面活性剂囊泡的处方和工艺[J].武警医学,2016,27(6):557-560.
-
2潘永梅,陈志强,贾蕊,马赟,郭倩.活血化瘀通络中药对糖尿病肾病大鼠肾小管间质纤维化的影响[J].中华中医药学刊,2017,35(8):2105-2108. 被引量：17
-
3吕春燕,杨天林,李进辉,吴程,王丽,陈昌金,赵梓亦.PEDF、END在UUO肾组织的表达及ADSCs对其的影响[J].中国现代医学杂志,2018,28(2):20-25.
-
4古文清,潘文斌,朱茜,肖潇,赵岩岩,刘雅琴,刘俊,李明.KIF3A在单侧输尿管梗阻小鼠肾脏中的表达及意义[J].南方医科大学学报,2020,40(2):219-224. 被引量：1
-
5王佳祺,张令歌,孙明姝,李勋亮,孙建平.1,25- (OH)2D3对大鼠肾纤维化的影响及其机制[J].青岛大学学报（医学版）,2020,56(6):640-644.
-
6庄娇容,林萍,邓小蕾.慢性肾病患儿25-羟维生素D3与蛋白尿及肾衰进展的关系[J].解放军医学院学报,2020,41(11):1085-1089. 被引量：3
-
1赵一.中西医结合治疗肝硬化血小板减少症的体会[J].现代中西医结合杂志,2008,17(24):3831-3832.
-
2徐顺清,舒柏华,姚大纯.氟对骨形态发生蛋白诱导软骨和骨形成的影响[J].中华劳动卫生职业病杂志,1997,15(3):154-156. 被引量：2
-
3赖小希,丁国华.牛磺酸对白蛋白诱导的鼠肾小管细胞凋亡的保护作用[J].中华肾脏病杂志,2007,23(9):600-601. 被引量：1
-
4杨继红,郑法雷,吴华,苏震,段琳,李艳.胰岛素样生长因子-I对体外培养的肾小管上皮细胞表型转化的作用[J].基础医学与临床,2005,25(5):459-464. 被引量：4
-
5宋青,胡媛芳.环孢素A对Tamm—Horsfall蛋白诱导的大鼠肾小管间质性肾炎的防治作用[J].中华肾脏病杂志,1993,9(3):136-138. 被引量：2
-
6王凤娇,马宏,李素仙,潘丽丽,李伟,王成礼.骨化三醇对单侧输尿管梗阻大鼠肾小管上皮细胞转分化影响的研究[J].中国药物与临床,2013,13(4):443-446.
-
7徐顺清,包克光,舒柏华,姚大纯.镉对骨形态发生蛋白诱导软骨和骨形成的影响[J].中华预防医学杂志,1997,31(5):292-294. 被引量：4
-
8任广慧,肖旭,石文达,张炎,陈健茂,姚青,李红兵,高岭.羊源Ⅱ型胶原蛋白诱导关节炎模型相关指标的检测[J].宁夏医科大学学报,2011,33(1):20-23. 被引量：1
-
9何攀,丁雪冰,朱清,阎磊,巴黎,邵凤民.Notch信号通路抑制剂对白蛋白诱导的肾小管上皮细胞凋亡的保护作用[J].中华肾脏病杂志,2013,29(12):934-935. 被引量：3
-
10王艳,孔祥阳,安海彬.经皮二尖瓣球囊成形术瓣口面积及血流动力学改变间相互关系的研究[J].临床医学,1999,19(4):34-35.
